34 results
The primary aim of this split-mouth randomized clinical trial is to assess accuracy of bracket positioning of a fully digital IDB workflow compared to a DBB workflow, with IDB bracket planning serving as reference for both methods. The secondary…
The aim of the study is to measure the effect on pain during needle-related procedures using VR hypnosis glasses versus hypnosis by a health care professional. Secondarily, anxiety, blood pressure, heart rate and patient satisfaction are measured.
The primary goal of this study is to compare ultrasound-guided ANB with FHB for analgesia during closed reposition of distal forearm fractures. Secondary goals are evaluation of feasibility in the ED regarding time and procedure success rate.…
Development of a diagnostic algorithm that will diagnose measles cases and classify (potential) contagiousness of patients following measles infection.
To investigate the influence of air temperature and humidity on the occurrence of EILO. A better understanding of the pathophysiologic principles causing EILO could lead to increased sensitivity of CLE testing. New insights in the causes of EILO can…
In this study, we hypothesize that the reference product (SalbR/Ventolin) is more effective than SalbG (Salbutamol Sandoz) atimproving the lungfunction in children with asthma, and that this difference increases alongside the severity of the airway…
Primary:To assess the effect of bilateral treatment with AAV5-hRKp.RPGR on functional vision as measured by vision-guided mobility assessment.Secondary:To assess changes after treatment administration in retinal function, functional vision, visual…
This study has been transitioned to CTIS with ID 2022-501677-39-00 check the CTIS register for the current data. Evaluation of patient and functional graft survival of adolescent renal allograft recipients converted from CNI to belatacept-based…
The primary aim of the proposed study is to test the effectiveness of CBT + ERT in reducing depressive and anxiety symptoms against CBT alone in adolescent patients (aged 13-19) with depressive or anxiety disorders in a randomized controlled trial (…
This study has been transitioned to CTIS with ID 2023-510160-12-00 check the CTIS register for the current data. To assess if venetoclax combined with FLA+GO (fludarabine, high-dose cytarabine, and gemtuzumab ozogamicin) will improve overall…
Evaluation of the effect of different treatment thresholds in a clinical pathway for children with acute asthma who are treated with supplemental oxygen
This study has been transitioned to CTIS with ID 2023-504593-38-00 check the CTIS register for the current data. The aim of this trial is to infuse multiple doses of human 1st trimester liver-derived MSC for the treatment of severe OI to determine…
The objective of this study is to elucidate unique and shared impairments across a broad range of social cognition tasks (at the behavioral, neuropsychological, and neurophysiological level by means of EEG recordings) related to subdimensions of…
The two objectives of this study are: 1) validation of two questionnaires, the Misophonia Screening List - Child and Youth and the Amsterdam Misophonia Scale-Youth (AMISOS-Y) in order to screen adequately for misophonia2) testing the effectiveness…
To evaluate the (cost-)effectiveness of a new patient-empowered FU protocol in patients with AIS that is based on patient-reported outcome measures (PROMs), self-assessment tools and physical examination, which is compared to standard or usual FU…
This study has been transitioned to CTIS with ID 2024-510578-25-00 check the CTIS register for the current data. Primary objectives:- To evaluate whether the outcome in children, young people and adults with HR-MB is improved over standard therapy i…
Our aim is to characterize ASMD patients* breath profile, exhaled breath and condensate as compared to healthy controls to identify specific volatile and non-volatile compounds that reflect inflammatory processes, fibrotic processes or sphingolipid…
The impact of communication possibilities on psychosocial difficulties in children with hearing loss
The primary objective of this study is to determine the effect of specific communicative abilities (speech recognition in noise; vocal emotion recognition and emotion expression) in children with hearing loss on their psychological (emotional and…
PRIMARY OBJECTIVE: -To assess the antibody response after mRNA (Pfizer, Moderna) SARS-CoV-2 vaccination in children with cancerSECONDARY OBJECTIVES:To assess in children with cancer after SARS-CoV 2 vaccination:- durability of the antibody response…
The goal of this study is to examine the feasibility of a home-based VR intervention to improve upper limb functionality in patients with CP. Primary research question: 1. Is VR-based gaming a feasible method to provide a rehabilitation intervention…