3732 results
The primary objective is to demonstrate superiority in overall survival of amrubicin (40 mg/m2 administered as a 5-minute infusion once daily for 3 consecutive days starting on Day 1 of a 21-day course) compared with topotecan hydrochloride (…
To study the effects of Mindfulness training in adults with ADHD on ADHD symptoms and comorbidity with affective and anxiety symptoms. Also, the feasibility of Mindfulness training will be evaluated in this specific patientgroup and the effect on…
To assess whether close rectal restorative proctocolectomy with IPAA has a better outcome regarding postoperative vaginal vasocongestion and reported psychological and sexual functioning then IPAA by TME restorative proctocolectomy.
Primary:to assess the reduction of initial study drug Cmax after administration of 20 mg study drug 10% SRF using three modified formulations as compared to the current Phase 3 formulation in healthy volunteers.Secondary:to assess the safety and…
To study the effectiveness of gut-directed hypnotherapy in the treatment of IBS-like symptoms in patients with inflammatory bowel disease.
The aim of this study is to demonstrate which is the most effective operation for neonates with necrotizing enterocolitis (NEC): intestinal resection with stoma formation or intestinal resection with primary anastomosis.
Primary objectiveThe objective of this pilot study is to test the hypothesis that the use of individual head supports will result in an actual given dose to both the target volumes as well as organs at risk that corresponds better to the planned…
The general objective of this project is to evaluate, for persons with a SCI, on the short and long term, the added value of a behavioural focused intervention, on top of a physical exercise intervention, on the level of everyday physical activity.…
To determine the safety and effectiveness of the PROMUS Element* Everolimus-Eluting Coronary Stent System (Boston Scientific Corporation [BSC], Natick, MA) for the treatment of patients with up to 2 de novo atherosclerotic lesions
How friendly is Delta-dry to the skin versus regular padding?Will Delta-dry be more functional than regular padding in patient experience? (Functional as in daily activity's concentrated to getting wet of the cast) How is the processability of…
The objectives of the study are:Developing an experimental design to obtain empirical data about the effects of a drama intervention on anxiety and mood disorders of adolescents.
The objective of this prospective randomised multi-center study is to compare the clinical outcome of the cemented and hydroxy-apatite coated uncemented hemi-arthroplasty for patients with a proximal intracapsular femoral fracture and the indication…
The project has two principal aims: (1) to assess the relative effectiveness of the three interventions, also as a function of patient characteristics, and (2) to delineate the functional and neurophysiological changes that are associated with those…
The primary objective of the study is to demonstrate a difference in changes in fasting blood pressure and 24-hour ambulatory blood pressure after 4 weeks on a diet with a high protein content or a diet with a high carbohydrate content.Secondary…
To compare visual outcome and foveal function after (initiation of) treatment between patients receiving an RPE-choroid graft and patients with anti-VEGF medication.
The purpose of the study is to evaluate the effectiveness and acceptability of the hot fluid balloon endometrial Thermablate ablation system compared with the Bipolar RF Novasure ablation treatment performed in an outpatient setting in eliminating…
The primary objective is to investigate if the use of the Online Exercise Coach enhances compliance with the follow-up exercise program. Therefore the primary objective is: 1. Are patients who used the OEC during their follow-up exercise treatment…
To randomly compare the effects of vessel sealing LigaSure on the operative parameters, post-operative pain and recovery and post-operative function of the pelvic floor in vaginal hysterectomy,
1: Comparing the initial and long term clinical results and survival of the Vanguard Deep Dish prosthesis with the traditional Vanguard Fixed bearing prosthesis.2: Does Joint Care improves the recovery process?
If negative pressure wound therapy reduces the period of wound healing with 2 weeks till 6 weeks, instead of 8 weeks ( all are approximate values), it can be the standard therapy in the future.