729 results
• To assess the added predictive value to known clinical predictors of a questionnaire that generates bleeding scores during pregnancy with regards to predicting (major) obstetric haemorrhage. • To describe the associations of haemostasis and…
To examine whether culprit lesion only percutaneous coronary intervention (PCI) with subsequent staged revascularization is beneficial over immediate multivessel revascularization by PCI for patients with cardiogenic shock complicating acute…
The primary objective of the Phase I portion of the study is the following:* To estimate the maximum tolerated dosing schedule for venetoclax given in combination with R-CHOP or G-CHOP to patients with B-cell NHL, either previously untreated or…
To evaluate the benefits, risks and costs of laparoscopic gastrectomy as an alternative to open gastrectomy (gold standard) as treatment for gastric cancer in a Western population.
To demonstrate the presence of a reduced age specific ovarian reserve status in BRCA mutation carriers by:1. using serum AMH as ovarian reserve status test. 2. using the antral follicle count (AFC) as ovarian reserve test3. using ovarian response to…
Primary Objective: To study arterial vessel wall abnormalities of the intracranial vessels (circle of Willis and its main branches and the moyamoya vessels) in patients with MMV in comparison with age- and sex-matched subjects without known…
Does pulsatile blood flow during cardiopulmonary bypass lead to a reduction in the average increase in postoperative creatinine levels in patients with preoperative renal dysfunction when compared to non-pulsatile blood flow?
The objective of this study is to evaluate the efficacy of oral cabozantinib at adaily dose of 60 mg compared with 140 mg in subjects with progressive,metastatic MTC.
Main objectieve of this study is if EMDR is an effective treatment for women with FoC. Our hypotheses are that in follow-up measurement compared to the pretreatment-measurement 1) WITHIN the treatment group there will be a decrease in the severity…
Primary objective: To assess microbiological, immunological, genetic, clinical, cognitive-behavioral, and epidemiological determinants for development of persisting symptoms in both adult and juvenile Lyme patients, and establish prediction rules *…
To determine which insemination technique in AID (IUI or ICI) is more (cost) effective in terms of ongoing pregnancy leading to a live birth.
The primary objective is to compare the incidence of patient-ventilator-asynchrony during paediatric mechanical ventilation using ventilator waveforms with PVA detected by using the ventilator waveforms in combination with diaphragm and intercostal…
Current practice variance in adult patients with chronic rhinosinusitis with nasal polyps (CRSwNP) is not efficient. Endoscopicsinus surgery (ESS) is the most common ENT operation in adults in the Netherlands. The objective of the present study is…
The main objective of this treatment protocol is to study the efficacy on the treatment response after adding a single gift of Mylotarg. Furthermore, monitoring of toxicity and long term efficacy is also important.
The main objective is to assess hallmarks of protective and waning immunity to vaccine preventable and non-preventable viral and bacterial diseases.in cases of various age groups and age-matched healthy controls. Secondary objectives are 1) to…
1. Evaluation of neurocgnitive functioning in children with HIV in comparison with healthy siblings using questionnaires.2. Qualitative analysis of different determinants that play a role in school participation in children with HIV using interviews…
Primary Objective(s): 1. Number of positive patients (as determined following histopathological analysis of the excised nodes).Secondary Objective(s): Collection of the below summarized information will provide us an answer to the following…
To investigate the feasibility of a 10 week (maximum) gait training with DFES in rehabilitation starting in the sub-acute phase after stroke and the initial efficacy on the recovery of spatiotemporal parameters, gait kinetics and kinematics,…
The primary objective of the main non-inferiority study is to determine the safety of TACmono starting nine months after kidney transplantation in immunologically low-risk patients in terms of BPAR-rate 15 months after transplantation compared to…
The rationale for performing this clinical study is to gather clinical data to evaluate the safety and effectiveness of the NUsurface device compared to the Standard of Care.