842 results
It is our hypothesis that one week of plaster cast treatment will give a better functional outcome score as Patient Rated Wrist Evaluation (PRWE) and a lower pain score at 6 weeks post injury and will be less costly as compared to the control group…
The goal of this research project comprises two important components that are intricately related:1) To define the pathophysiological state of the peripheral motor pathway in patients with SMA and to determine the contribution of the constituting…
To investigate if a high loading dose of 2 grams paracetamol has a beneficial effect on pain sensation or has an opioid-sparing effect in patients with pain in the Emergency Department
Primary objective: The primary goal of this research is to compare peri-implant hard tissue around implants placed using a modified drilling protocol, i.e. a reduced drilling speed without cooling and around implants inserted using a default…
The main objective of the study is to investigate if sleep positional therapy, using the LEFT, reduces nighttime gastroesophageal reflux symptoms.
To prove that sustained clinical remission can be maintained at week 14 with a new dietary strategy that involves only 2 weeks of EEN with Modulen and 22 weeks of an exclusion diet involving selected table foods. We hypothesize that use of EEN for…
Primary Objective: The aim of this study is to compare if an online consultation with diagnostic testing during a fertility workup, is as effective as a regular consultation in terms of patient centeredness, shared decision making and costs.
To assess a pilot-study on the impact of removal versus preservation of the pectoral fascia on total drain volume, time to drain removal and needle aspirations (and thus seroma) in women undergoing bilateral prophylactic mastectomy.
Primary objectiveTo assess the safety and tolerability after single and multiple intravenous administrations of PPSGG in patients suffering from anti-MAG neuropathy.Secondary objectives- To evaluate the PK of PPSGG after single and multiple…
The objective of this study is to evaluate the feasibility and to determine the preliminary effects on physical functioning, muscle function, body composition and postoperative recovery of a combined preoperative nutrition and exercise intervention…
To assess the safety and effect of edoxaban in Chil-Pugh B cirrhosis.
Primary Objective: To identify the variability in the circulation of the number of patrolling monocytes and their expression of CX3CR1 obtained from adult ZZ-AATD patients compared to spouse controls.Secondary Objective(s): (1) To identify if low…
Primary Objective: This study aims to analyze cycling gross efficiency, pedalling power symmetry, and hip, knee, ankle kinematics in adults with a transtibial amputation in different foot positions and seat heightsSecondary Objective(s): The second…
Primary objective:Does addition of azithromycin to standard chloroquine treatment result in a higher clinical cure rate at day 7 than treatment with chloroquine alone in patients with COVID-19.Cure is considered when 4 criteria are present:(1) O2…
Using epigenetic, transcriptional, metabolomic and proteomic approaches in cardiac and skeletal muscle tissue, we want to reveal distinct biological pathways affected in ACM, DCM and PLN r14del cardiomyopathy.
Primary Objective:Delineate the differences in cellular composition and function at the maternal-fetal interface in patients with SLE compared to healthy women Secondary Objectives:- Establish a novel in-vitro model to study cell-cell interaction at…
The main study objective is to examine the effect of the PTWD program on glycaemic control of lower-educated participants with T2D. The secondary objectives include the effect on medication use, use of care and T2D self-management behaviours. We…
In patients diagnosed with a hip fracture who also have acute myocardial injury on presentation to hospital, is accelerated surgery superior to standard care for the primary outcome of death at 90 days after randomization?
To evaluate the effect of triple-therapy wih Budesonide, Glycopyrronium and Formoterol Fumarate (PT010) versus dual therapy with Budesonide and Formoterol Fumarate on asthma exacerbations in adult and adolescent subjects with inadequately controlled…
Primary Objective: To evaluate cytokine levels in blood samples of human subjects with tinnitus and normal hearing, compared to healthy controls.Secondary Objective(s): To evaluate complete blood count measures (neutrophil count, platelet count etc…