833 results
Primary objective of the study is to determine the effect of 2 different treatment strategies of vitamin D supplementation on 25(OH)D3 serum concentration after 12 months of supplementation. Secondary objectives are to determine the effects on the…
The purpose of the study is to evaluate the usability of PatientCoach by patients with asthma and/ or COPD,hypertension and/or Diabetes Mellitus.
What is the functional status of patients who have been treated using the dogbone Button technique as surgical treatment or by means of conservative treatment of acute acromioclavicular luxation at least 3 months and up to 24 months after surgery?
To evaluate the long-term (up to 5-years after procedure) efficacy and safety of CA against SA in preventing the recurrence of LA arrhythmias in patients with a history of paroxysmal and/or persistent AF
The purpose of the study is to investigate the ability of MYL-1401H to evoke an immune response (immunogenicity) as compared to Neulasta® US. In addition, the effect of MYL-1401H on blood cells as compared to Neulasta® US will be investigated. The…
To validate and compare smartphone-connected blood pressure monitors produced by Withings, Qardio and iHealth with the gold standard and a validated automatic blood pressure monitor.
Primary:• To evaluate the safety of RejuvenAir Cryospray therapy to treat symptomatic chronic bronchitis patients with airflow restrictions• To evaluate the feasibility of the planned liquid nitrogen cryospray treatment.Secondary:• To evaluate…
The primary objective of the study is to explore and compare the signal strength of different probes for measuring pulse oximetry signals on different body locations. The secondary objective of the study is comparing aspects of user experience (via…
The purpose of this prospective post market observational pilot study is to evaluate the effect of DRG stimulation in the management of chronic discogenic pain in subjects who are refractory to other available treatments. Selected subjects will not…
Primary objectiveTo evaluate the change in quality of life (NEI VFQ 25) in subjects with DME during the first year of treatment with aflibercept according to the EU label for DMESecondary objectives• To assess further the safety and tolerability of…
To determine the efficacy of quantification of vitreous floaters captured by SLO-imaging technique for Nd:YAG vitreolysis for persisting vitreous floaters.
The purpose of the study is to investigate how quickly and to what extent JNJ-63623872 is absorbed, distributed, metabolized (broken down) and eliminated from the body (this is called pharmacokinetics). The compound to be administered will be…
The study is designed to evaluate the possible association between genetic variants and susceptibility to IRF, based on previous studies in autoimmune-inflammatory diseases (celiac disease, type 1 diabetes and rheumatoid arthritis).
In the current study we aim to assess the energy requirements and physical activity patterns in professional soccer players along with their nutritional intake patterns. As such, this study will provide valuable information to optimize the…
To assess safety, tolerability and pharmacokinetics of a single subcutaneous administration of HPV-NIRD1.
1. to determine the feasibility and acceptability of an e-supported lifestyle coaching program and2. to assess the effects of personalized lifestyle support in patients with insulin dependent type 2 diabetes mellitus immediately after 12 weeks and…
The main objective of this study is to answer the following question: What is the prevalence of child maltreatment amongst high school students in the Netherlands. Secondary objectives are the determination of the prevalence of subtypes of child…
Primary objective * To determine the maximum tolerated dose and recommended dose of metformin plus chloroquine in patients with IDH1/2MT glioma, IHCC and CS Secondary objectives * To describe the toxic effects of metformin plus chloroquine in…
To validate two novel genomic biomarkers that provide information with respect to the presence of PCa, disease aggressiveness, and progression towards recurrent and metastatic disease.
A new method, implemented in the I-Space Virtual Reality application, will be tested on its reproducibility and validity. It will be used to describe fetal movement patterns. This new method can improve the rapidity of fetal movement studies and…