6936 results
The aim of the project is to study the effect of "UCB1577571 en CA050_01953" on typical skin features of psoriasis. This information can establish the most effective compound, right formulation and dose for further clinical research.
The main objective is to investigate the preparatory process in left primary motor cortex in relation to hand choice during whole-body motion.
To evaluate the effects of tDCS on information processing speed in comparison to sham tDCS in patients after stroke with ascertained reduced processing speed. A proof of principle study.
To assess the correlation between the presence of GIP in urine/ faeces and symptoms after a single dose gluten provocation (mimicking the daily risk of gluten ingestion) in patients with coeliac disease adhering to a strict gluten-free diet.
The aim of this study is to evaluate the long-term imaging and functional outcomes of overuse injuries of the wrist in (former) athletes.
PrimaryObjective 1: To evaluate the effects of ENG and E2 on ovarian function (pharmacodynamics) when the ENG-E2 vaginal ring (MK-8342B) is used for an extended period of time (i.e., 35 days) in healthy young adult female subjects.Objective 2: To…
To explore the extent of inter- and intrafraction anatomical changes of the tumour and surrounding normal tissues, throughout the full course of treatment, and to subsequently assess the impact of these changes on the nominal planned dose. This…
This is a follow-up (FU) study for subjects who completed Study ALX0681-C301 (HERCULES) according to the protocol (i.e., completed the Final [28 day] FU visit). Subjects who completed Study ALX0681-C301 will be given the option to participate in…
1. To investigate non-invasive 4D flow CMR for the assessment of aortic arch stenosis and compare and correlate this to conventional imaging modalities and to three-dimensional rotational angiography (3DRA) with computational fluid dynamics (CFD). 2…
The purpose of the study is to investigate how quickly and to what extent BIM23B065 is distributed, metabolized (broken down) and excreted from the body, and what the main route of excretion from the body is (urine or feces); this is called…
The objective of this clinical investigation is to evaluate the clinical performance of Provox Luna in comparison to the usual care of the patient.
Study i)Select the most valid and feasible accelerometer for measuring habitual physical activity in children with a mitochondrial disorderStudy ii)Measure the test-retest reliability of this instrument
This study aims at establishing the influence of sampling site on the variability of ACT measurement at the end of coronary angiography or PCI.
1. To investigate short- as well as long-term outcomes in patients who underwent CAWR in the Academic Medical Center and St Marks Hospital London between 2004 and 2015 with hernia recurrence as primary outcome. Secondary outcomes involve morbidity,…
The primary objective of this study is to predict the antidepressant treatment outcome of ECT in patients with severe depressive symptomatology using neuroimaging. ECT itself is conducted as usual according to national guidelines (Nederlandse…
The aim is to investigate the feasibility of DBS from finger prick for measuring infliximab drug levels and ATIs compared with the results of venepuncture serum sample measurements. As a secondary objective, measurements of albumin and CRP will also…
Zie document PROTOCOL SYNOPSIS ABC study
The objective of this study is to obtain physiological data on lung aeration during pulmonary transition in newborn infants.
Step 1 Primary objective: To describe the population pharmacokinetics of flucloxacillin for non-critically ill patients and determine the influence of covariates (demographics and renal function) on the kinetics of flucloxacillin. Step 2Primary…
To evaluate the effects of long-term intranasal oxytocin on social behaviour in children with PWS and to compare the effects of different doses and frequencies of oxytocin administration