49 results
The primary aim of the study is to assess the prevalence of MDRO carriage in patients undergoing ERCPs. This will be performed in four different countries with expected significantly different prevalence rates of MDRO carriage, namely: India, United…
The main objective is to investigate the heterogeneity of type 2 asthma by identifying phenotypes by means of cluster analysis. Secondary, the clinical interpretation of these clusters is investigated.
Our primary objective is to determine the prognostic value of parameters for early disease detection of familial pulmonary fibrosis in the study population. All putative parameters for detection of preclinical disease have been shown to be…
Clinical Trial Protocol section 2.The main objectives of the trial are to assess the safety and tolerability of two doses of ABNCoV2, formulated with and without the adjuvant MF59, in healthy adult volunteers and to identify the dosage and…
To study the effect of individual control of the light on thermal comfort
To determine the accuracy of computational fluid dynamic models for the quantification of the pressure gradient of tandem stenoses in the femoropopliteal artery, as compared to invasive pressure measurements.
• To set up a national prospective observational cohort study of patients who have a hematological B-cell malignancy and are referred to the national CAR T-cell tumorboard for evaluation of eligibility for treatment with CAR T-cell therapy and to…
Our main aim is to validate the TiMaSCAN as both a diagnostic and monitoring tool in the treatment of pulmonary exacerbations in CF patients.
To establish the effectiveness and safety of EUS-CD as the primary drainage strategy in patients with malignant distal biliary obstruction.
Primary* To explore the pharmacokinetics of insulin aspart after pulsed intra-vaginal delivery using the MedRing and after subcutaneous injection in women with DM1.Secondary* To assess the safety and short-term tolerability of insulin aspart after…
This study aims to: 1. Determine the role of early neurocognitive functioning in the outcome from ABI in rehabilitation, as defined by the level of neurocognitive functioning, participation and quality of life at six months after start of the…
Primary Objective: To test clinical safety of PNMP up to 6 hours as a modality to assess viability and evaluate initiation of tissue repair ex-situ in donor kidneys prior to transplantation.Secondary Objective(s): To monitor standard and novel renal…
The primary objective is to study if PC surveillance in individuals with a CDKN2A or other high risk mutations leads to an increase of 5-year survival rate, as compared to PC in the general population. Secondary objectives are: (1) to study long-…
To assess the effect of Virtual Reality mediated visual and auditory lowering of electrical pain detection and tolerance thresholds
To assess the risk profile associated with the combined endpoint of all-cause mortality and HF hospitalizations in HF patients with LVEF >0.40.
To collect long-term, real world data on safety and efficacy of gene therapy with voretigene neparvovec (Luxturna®).
Rotating low-field MRI offers the opportunity to visualize the neck veins in different positions to study how these pathways differ with alternating body positions. For low-field MRI no standardized non-contrast-enhanced protocol is developed to…
The main objective of this study is to conduct a double-blind randomized control trial to assess the efficacy of 3 different amplification schemes of hearing aids in tinnitus patients. The schemes will be adjusted to the individual*s tinnitus…
Objective: The primary aim of the current study is to assess the effectiveness of a narrative group intervention for recovery in persons with PDs.
Evaluate the safety and feasibility of providing automated tactile stimulation in response to apnea, bradycardia and/or desaturation using the BreatheBuddy.