Search for a trial

Pharmacokinetic study to assess the bioavailability of phenolics from an olive leaf extract

The objective of the study is to obtain information on the bioavailability and pharmacokinetics of the phenolics present in an olive leaf extract (Bonolive®, dose 250 mg), standardized on 40% oleuropein, and to identify the composition of the…

Contrast-enhanced MR imaging of the breast at 7T and 3T in the same patients.

The objective of our study is to to assess the diagnostic performance of 7T CE breast MRI in comparison to the current clinical standard of 3T MRI and histopathology on a intra-individual basis.

Flavour nutrient learning of vegetables

To understand more of the learning principles of vegetable consumption in young children (2-4 years). The aim of this study is to investigate the effect of flavour nutrient learning on vegetable preference and intake. Primary Objective: To…

Predictive diagnostic study on the short-term metabolic effects of recombinant human Growth Hormone treatment in growth hormone deficiency and small for gestational age children.

The primary objective of this study is to assess the relation between the short term metabolic changes after start of rhGH therapy and the long term change in height SDS after one year of treatment. Secondly, we want to assess the effects of GH on…

Effect of administration route on the pharmacokinetics of cobalamin in elderly

Establishing the pharmacokinetics of intranasally and intramuscularly administered cobalamin in elderly.

Threonine requirement in preterm neonates

The aim of the study is to quantify the requirement of threonine in preterm infants. We hypothesize that the current estimations for preterms are too high.

*Why does the number of bites affects satiation? A possible role for cognition**

The objective of this study to investigate the role of attention on the effect of NB on ad libitum intake.

Optical Tissue Stylet - descriptive observational study into paravertebral space detection in humans

The primary objective of the trial is to investigate if the optical tissue stylet technology can reliably identify the thoracic paravertebral space. Diffuse reflectance spectra will be acquired during needle advancement, with custom-made needle…

Mood Radar: a technical aid in monitoring upcoming challenging behavior. Discovering dependable predictors of upcoming challenging behaviour in people with a mental disability. Measuring physiology of clients and their caretakers in natural situations. Viewing Challenging behaviour from a bio-physiological transactional model.

The primary objective of this study is to investigate the physiology of clients with ID and their caretakers in naturalistic situations in relationship to the occurrence of challenging behavior. The level of arousal in daily situations will be…

Investigating oral processing in relation to taste and texture of (semi-)liquid foods

The primary objective of this study is to identify specific oral processing movements and/or patterns that occur during consumption of (semi-)liquid foods, with respect to taste and texture related properties (e.g. taste intensity and viscosity),…

Prevalence and biomarkers of pre-cachexia and cachexia in advanced cancer patients scheduled for treatment with chemotherapy

- To determine the prevalence of (pre)cachexia - To determine whether potential biomarkers of pre-cachexia can be identified

Comparison of pre- and postoperative clinical target volumes at CT and MRI imaging in breast-conserving therapy: A prospective cohort study.

To detemine the optimal imaging modality and moment in time to delineate RT target volumes in breast-conserving therapy.

Spinal cord stimulation for treating neuropathic pain after chemotherapy / radiotherapy; a pilot study

To demonstrate that SCS is capable of treating otherwise refractory neuropathic pain after chemotherapy / radiotherapy.