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Cholesteatoma disease recidivism after canal wall up tympanomastoidectomy with or without obliteration: a randomized controlled trial (CLEAR-EAR).

The primary aim of this study is to investigate whether a canal wall up (CWU) tympanomastoidectomy with obliteration of the mastoid and paratympanic or epitympanic spaces reduces cholesteatoma recurrence and residual rates compared to the same…

Effects of daily protein supplementation on brain function in older adults with overweight or obesity

The primary objective is to investigate in overweight or obese older adults the effect of daily protein supplementation for two weeks with either a plant-derived protein or an animal-derived protein on vascular function and insulin-sensitivity in…

Extended pouch gastric bypass vs one anastomosis gastric bypass in patients with BMI>=45

In this single-blinded randomized controlled trial the investigators aim to compare the OAGB and the EPGB in terms of percentage total weight loss (%TWL) 1 and 3 years postoperatively, postoperative complications and comorbidity remission in…