13 results
Primary objective:- To investigate if neo-adjuvant combination of talimogene laherparepvec and nivolumab will achieve a pathologic response rate of 45% complete responses (either *pathological complete response (pCR)* or *pathological near complete…
The primary objective is to examine whether changes over time in monitoring measures of cognition and behavior are associated with functional outcomes in pediatric oncology groups. Additional objectives are to examine trajectories, risk factors, and…
OpACIN-neo:Primary objectives: - To compare safety (immune related adverse events during the first 12 weeks) of three different neo-adjuvant combination schemes of ipilimumab + nivolumab - To compare radiological and pathologic response rates at…
Primary Objective:1. To validate the HLA-DQ typing in blood taken by a fingerprick; to make it feasible in the regular Preventive YHCCs organization.2. To establish the feasibility of HLA-DQ2/8 typing in the active case-finding at the Preventive…
Objective: To evaluate the usability (feasibility) of the recently developed tool 'NutriProfiel focused on athletes' so that opportunities can be explored for further improvement and implementation in practice.
The objective of this study is to determine what the differences are between care as usual and care where a seizure detection device is used in addition to care as usual. Specifically, this study will compare the number of missed and correct visits…
Primary objective:Can a personalised lifestyle intervention (LIFE-ID intervention) support healthcare professionals in achieving effective and long-term lifestyle improvement (increased physical activity) for adults with ID to improve their&…
To develop a tailored care pathway for RDPC that ensures effective use for pregnant women in vulnerable circumstances.
Determine AYA*s experiences and needs related to FP(C) and follow-up care after FP(C) (Q1); determine the number of AYAs pursuing to conceive and their fertility and obstetric outcome(s) after FP(C) after gonadotoxic treatment (Q2); determine…
Objective 1: To assess the effect of implementation of a dashboard, with (near) real-time data feedback of risk stratification tools and care processes, on relevant clinical outcomes (in-hospital mortality, ED-LOS, admission rate) and discrepancy…
This feasibility study will now evaluate its use during regular visits, gathering feedback from parents and YHCP, along with user data from the digital tool.
Objective 1: To assess knowledge, attitude health-care professional satisfaction andperceived barriers and facilitators of use and implementation by health care professional inthe ED.Objective 2: To assess process of care and outcome indicators…
This study aims to examine how senior year medical residents from different specialties in the Netherlands understand and apply the legal framework for reporting possible child maltreatment. Moreover, we aim to understand the threshold to report a…