20 results
Primary Objective:- To assess lipid levels of STEMI patients over a long course. Secondary Objectives:- To assess the association between poorly controlled cholesterol and (apo) lipoprotein levels for the long term outcome in STEMI patients.- To…
Is, when EE is kept constant, replacing sitting time by NEA more effective than exercise in improving glucose control in people with DM2?
Examine the impact of 7-day daily ischemic preconditioning on brachial artery endothelial function (measured as FMD%) in the dominant arm (i.e. local effect: primary objective) and contra-lateral arm (i.e. remote effect: secondary objective) in…
To examine the impact of age and physical fitness on the ability of ischaemic preconditioning to protect endothelial damage in response to ischaemia reperfusion injury in healthy humans. A secondary objective is to explore the role of Toll-like…
The objective of the study is to compare the effects of homogenized, unhomogenized and skimmed milk with butter on postprandial metabolism in healthy overweight men.
The possibility to identify the risk of rupture of a carotid plaque will have tremendous impact in clinical decision making. Selection of candidates from surgery is based mainly on duplex ultrasonography, where now only the size of the stenosis is…
Our main objective is to determine the effect of HO-1 induction by heme arginate infusion on insulin resistance and endothelial dysfunction related to MetS. Secondary objectives are to determine the effect on adipose tissue, adiponectin plasma level…
In this trial, current usual care concerning cardiovascular education is described. Second aim is to study what is understood of this education by the patient. Last aim is to study what effect training of GP's on this subject will have on the…
The objective is to study whether saturated fatty acids induce a different postprandial change in inflammatory markers than cis-polyunsaturated fatty acids.
To demonstrate the efficacy of a PTFE covered stent-graft in the prevention of outflow re-stenosis in loop fistula in a prospective trial.
The main aim of this implementation research is to systematically screen all RA patients of Reade rheumatology and revalidation centre in Amsterdam for their cardiovascular risk profile and if necessary to treat them for cardiovascular risk factors…
To disclose the pathofysiologic basis of the favourable risk profile by measuring factors associated with cardiovascular disease.
The primary objective of this study is to assess the patient*s experience of performing home BP measurements themselves (feasibility) in the first month after carotid endarterectomy. Furthermore, the secondary objective will be the time from the…
Rationale:A study reporting the frailty trajectories after vascular surgery is currently lacking. The aim of this study is to evaluate the influence of the surgical intervention on the different domains of frailty, by measuring the characteristics…
The primary objective of this study is to determine the nutritional intake, nutritional status, and physical activity level at various moments post-lower limb amputation (i.e., during hospital admission for amputation, at 5 weeks post-amputation, at…
To determine the effect of a five-week vegetarian diet on innate immunity of patients with a recent myocardial infarction and healthy participants.
To determine whether plaques in young patients with familial hypercholesterolemia (aged below 50 years) are susceptible to significant plaque regression with early, aggressive lipid lowering therapy (statins, ezetimibe and/or PCSK9) according to…
Evaluate the natural history of coronary artery disease and evaluate whether mid- to long-term plaque progression and changes measured with CCTA imaging can effectively predict CV events.
Primary Objective:Our primary goal is to investigate the feasibility of a large pragmatic study of the effectiveness of a tailored MLI for patients with depression in general practice and to evaluate potential barriers and facilitators in a process…
1. To determine the influence of frailty on predicting an increase in HRQL in elderly peripheral vascular surgery patients. 2. To develop an 'AGE-VASC score' for predicting an increase in HRQL after cardiac surgery based on surgical risk…