33 results
In this study we will identify the role of the endothelial GAGs in Na+ and volume homeostasis. Is there a link between the ESL and an individual its susceptibility to Na+-excess?In a following study the Na+ buffering capacity of the intact ESL will…
Primary objectives of the pilot study• To determine childhood cardiovascular health in offspring of PCOS mothers and to compare it with children from non-PCOS mothers.Secondary objectives of the pilot study• To compare cardiovascular risk factors…
To investigate whether pRDN leads to a change in renal blood flow
To investigate whether increased aldosterone levels in obese individuals lead to impairment of microvascular function through reduction of NO-availability, and to establish the role of microvasculaire dysfunction in the pathogenesis of salt-…
In this study we aim to elucidate effects of dietary sodium intake on:1. Microcirculation by studying the capillary network during high and low sodium conditions.2. Adaptive and innate immune system by studying circulating T-lymphocyte…
1) to investigate whether hypertensive patients with WMLs decline more strongly in cognitive function than hypertensive patients without WMLs in a 4-year time period. 2) to identify predictors for cognitive dysfunction in hypertension/SVD patients.
To identify predictive variables correlated with percentage excess weight loss, reversal of metabolic complications of obesity and quality of life and postoperative complications; to identify metabolic variables correlated with markers of the…
We will investigate endothelial function before and after bariatric surgery.
The objective is to test the hypothesis that radiotherapy for lung cancer induces an increase in pulmonary artery pressure.
To investigate whether renal denervation leads to a decrease in oxidative stress in patients with therapy-resistant hypertension.
In this study, we will prospectively assess the association between serum CK and response to standard antihypertensive drugs (calcium blockers or monotherapy with other antihypertensive drugs according to the policy of the general practitioner).
The researchquestion of this study:Is there an association between the respiratory and cardiovascular system in early childhood? If there is an assocation, what are its determinants?
We will enable CEUS measurements of forearm skeletal muscle and determine the intra-observer and day-to-day variability in CEUS measurements.
Primary objective1.To determine the characteristics, frequency and severity of vascular, metabolic and hormonal side effects of angiogenesis inhibitors and EGFR inhibitors.Secondary objectives1.To investigate if steroid profile, indol profile,…
We will investigate how video microscopy compares to CEUS in its assessment of insulin-mediated vasoreactivity.
The goal of this study is examining the acute effects of insulin on microcirculation in hypertensive insulinresistant subjects and investigate if angiotensine II influences these effects. Amendement: The goal of the amendement is to exame the…
The aim of the study is:- To find simple clinical and/or laboratory parameters to predict the development of hypertension during treatment with the tyrosine kinase inhibitor Sunitinib. If such parameters are present it will be evaluated…
In the current study we want to evaluate the microcirculatory glyccalyx in patients presenting with malignant hypertension and relate this to patients with severe hypertension. Microcirculation is assessed using SDF imaging, oxygen supply using NIRS…
To investigate the difference between two meals (high in protein vs. high in carbohydrates) on the endothelial function?
To determine the cardiovascular changes in response to orthostatic stress in women with a vascular complicated obstetric history or recurrent miscarriage.