16 results
To evaluate the feasibility and potential of sentinel node biopsy in patients with (recurrences of) laryngeal carcinomas and clinically negative neck undergoing total laryngectomy and neck dissection.
Aim of studyTo investigate whether patients with disease eligible for (salvage) surgery would potentially benefit from immunotherapy, we want to study the anti-tumor reactivity of T cells that have infiltrated the tumor. Infiltration of T cells in…
Primary Objective1. Investigate the feasibility of intraoperative imaging with CBCT in open maxillectomy for verifying resection of the intended treatment volume. 2. Assess the feasibility of the intended treatment volume segmentation and resection…
This study has been transitioned to CTIS with ID 2024-514233-37-00 check the CTIS register for the current data. To evaluate the feasibility and prove the concept of sentinel node biopsy in patients with carcinoma of the parotid gland and scheduled…
(1) to create and train an algorithm to generate synthetic CT images of the craniofacial area(2) to evaluate the resulting synthetic CT images in terms of geometrical accurate visualization of the craniofacial osseous structures compared to the…
The primary objective is to clarify the frequency of t-BPPV in patients after mild TBI. Secondary objectives are: assessment of the symptoms of t-BPPV and the treatment success of t-BPPV.
The primary objective of this study is to assess the diagnostic accuracy, in terms of sensitivity and negative predictive value, of preoperative CT lymphography as compared with conventional lymphoscintigraphy for SLN detection. Secondly, we aim to…
We propose to use an alternative superparamagnetic tracer containing ironoxide, which can be detected with MRI and with a magnetic probe. The spatial resolution of MRI is superior to gamma camera detection. Moreover, there is no radiation exposure…
This study aims to explore the rate of contralateral lymphatic drainage and occult contralateral metastases in patients with lateralized OSCC, a clinically negative contralateral neck and clinical ipsilateral lymph node metastases metastases or a…
The primary objective of this study is to assess the diagnostic accuracy, in terms of sensitivity and negative predictive value, of preoperative 68Ga-Tilmanocept PET/CT combined with conventional lymphoscintigraphy for SLN detection. Besides, we aim…
Determining the feasibility of SLN detection in the neck of oral cancer patients using a magnetic tracer (Sienna+®), MRI and hand-held magnetometer (SentiMag®).When the magnetic approach of sentinel node detection is found to be feasible, the main…
The primary objective of this feasibility study is to investigate the detection rate of SLNs using MR lymphography.
Primary objective: The primary objective of this study is to compare the preoperative radiotracer kinetics (rate of injection site clearance and rate of SLN uptake) for Lymphoseek and 99mTc-Nanocoll. Secondary objectives: * To compare the number of…
The primary objective is to improve the accuracy to predict glioma genotype of our previously developed algorithm *PrognosAIs* by adding advanced MRI acquired before surgery. The secondary objective is to learn the relationship between MRI signal…
The primary objectives of this study are:* Analyse if shear wave ultrasound elastography with ElastQ and LASTIC are both feasible techniques to identify differences in tongue tissue elasticity and analyse if there is a correlation between both…
The next step is to personalize the model and validate the model using different modalities. These modalities are grouped into four subprojects. Finally, the results of the subprojects will be integrated within the biomechanical model so that a…