53 results
The aim of this study is to assess the clinical value of 99mTc-mebrofenin SPECT for the measurement of liver functional volume in patients planned for liver resection, in comparison to CT-volumetry. Furthermore, the significance of liver volume in…
Therefore, we aim to define the pattern of lymphatic drainage from each of the liver segments, using standard lymphangiography during planned partial liver resection, thereby creating a *drainage map* of the human liver.
Primary objective * To determine the overall response rate of two PHP with an interval of at least 6 weeks and 3 mg/kg melphalan in irresectable liver metastases patients.* To determine the percentage of patients qualifying for resection. Secondary…
To primary objective is to evaluate the clinical safety and performance of GATT-Patch in open liver surgery, in order to collect the necessary data to assess whether GATT-Patch meets the general safety and performance requirements for its CE marking…
To establish the effectiveness and safety of EUS-CD as the primary drainage strategy in patients with malignant distal biliary obstruction.
Primary:- The feasibility of SFR spectroscopy incorporated in an ERCP procedure.Secondary:- Determine physiological differences between benign and malignant biliary strictures, based on the obtained spectra acquired over a broad wavelength range (…
The aim of the study is to demonstrate that HAIP chemotherapy is an effective treatment for unresectable intrahepatic cholangiocarcinomas.
The primary objective is to compare efficacy of MWA to the efficacy of SBRT with regards to the primary endpoint (local tumour progression free survival at 1 year [1-year LTPFS]) in patients with unresectable CRLM (3 - 5 cm) that are unsuitable for…
Primary objective: To investigate the feasibility of using intraarterial ICG preoperatively to allow for liver segment visualization during anatomical liver resection.Secondary Objective(s): 1. To investigate the dosage which provides sufficient…
The primary objective of this study is to assess the feasibility of ultrasound-based navigation for assistance during hepatic resection. Secondary objectives are 1) to evaluate the ease of use and support for decisiveness during surgery, 2) to…
The primary objective of the study is to demonstrate safety and performance in reducing intra- and post-operative leakage (bile and pancreatic juices) by using the Sealing Device in patients undergoing elective hepatic resection or distal…
The aim of the study is to gain more insights into the metabolic demand and possible changes thereof pre- and postoperatively. Additionally, data on aerobic fitness and activity levels will be gathered.
Over recent years, post-processing software has become available that allows co-registration of pre- and post-ablation CECT. This allows three-dimensional quantitative assessment of ablation margins. Such quantification of ablation margin would…
To determine safety, tolerability, and activity of individualized radioembolization with 166Ho-microspheres combined with FTD-TPI and bevacizumab.
To assess the feasibility of CT based 3D preoperative resection planning for hepatectomy and postoperative resection confirmation through image fusion of pre- and postoperative 3D CT reconstructions.
The primary objective of this study is to compare efficacy of IRE to the efficacy of SBRT regarding the primary endpoint (local control at 2 years) in patients with perivascular and peribiliary CRLM (0-5 cm). The CRLM are unsuitable for surgery and…
Primary objective:To establish the safety and toxicity profile of individualized 166Ho-RE in patients with hepatocellular carcinoma. Secondary objectives:• To evaluate efficacy of individualized 166Ho-RE.• To evaluate biodistribution / dosimetry.•…
This study has been transitioned to CTIS with ID 2024-515525-28-00 check the CTIS register for the current data. The aim of this study is to prove feasibility of HAIP chemotherapy (floxuridine) in combination with standard systemic chemotherapy…
The aim of this study is to develop and evaluate a new ultrasound-based navigation system for guidance of resection and ablation of liver lesions during liver surgery. The feasibility and accuracy of this in-house developed navigation system is…
The main objective of this trial is to investigate the ability to visualize the exact location of left and right confluence of the bile ducts and thereby distinct between right and left hepatic ducts and the common hepatic duct using NIRF imaging.…