88 results
This study, comparing two cohorts, is designed to determine the postoperative residual mesorectum on MRI after TME. Patients with a clinical T1-3 rectal carcinoma (10cm or less from the anal verge based on preoperative MRI of the pelvis) who…
The study will collect data related to symptoms of recurrent biliary stent obstruction requiring reintervention, adverse events, and a variety of important secondary endpoints including technical success and time to symptomatic recurrent biliary…
1. comparison between pre- and postoperative serum levels incretines and bile acids (after RYGB).2. comparison between S-RYGB and LBPL-RYGB with respect to incretines and bile acids.
The primary objective is to describe the functional outcome of patients that choose for organ saving treatment.
To assess the safety and feasibility of curative esophagectomy combined with three field lymphadenectomy after chemo-radiation in Western patients with resectable thoracic esophageal carcinoma and cervical lymph node metastases in level III and/ or…
To compare midazolam pharmacokinetics in morbidly obese patients before/during bariatric surgery and 0.5-2 year after surgery.
The main objectives of this study are to evaluate the safety and performance of the AutoLap system in the following laparoscopic procedures: hernia repair, cholecystectomy, right colectomy, Nissen fundoplication and sigmoidresection. The AutoLap…
A new device has been developed in the VU University Medical Center enabling us to measure perfusion pressure in mmHg in the bowel wall or wall of the gastric conduit. Correlating this measurement to systemic blood pressure in mmHg subsequently…
This study aims to determine whether early start of oral intake in patients that underwent an esophagectomy is feasible and safe.
This study will be performed to evaluate the safety of the ACE stapler for the treatment of obesity. The secondary objective is to evaluate effectiveness of the ACE stapler for the treatment of obesity.
The primary objective of the ERY-PAO study is to investigate the pharmacokinetics of acetylsalicylic acid (ASA) and omeprazole in morbidly obese subjects before and after RYGB surgery and to compare these data to study if there are differences in…
The objective of this study is to investigate the amount of clinically relevant complications (defined by Clavien-Dindo score 3 or higher) caused by IRE in patients with locally advanced, non-resectable, non-metastasized, pancreatic cancer.
This is a feasibility study of the System to assess safety and performance in patients scheduled to undergo esophagectomy.
This study is performed in order to study the population pharmacokinetics and pharmacodynamics of propofol and nadroparin in morbidly obese patients with a total body weight higher than 170 kg. The recently developed and published pharmacokinetic…
The primary objective of this study is to investigate target site penetration of cefazolin in morbidly obese patients. Also, we aim to investigate whether cefazolin plasma concentrations are predictive of subcutaneous (target) cefazolin…
Determine the safety and preliminary efficacy of the new ACE Stapler in the specific tissue apposition application of repairing dilated post-surgical gastric anatomy over a 12 month follow-up period.
Objective of this research is to evaluate whether neo-adjuvant chemo-/radiotherapy in small non-advanced rectal cancers can be used to obtain a complete or near complete remission. In these patients could a complete resection of the rectum as an…
The primary objectives of this study consist of:1. To assess the accuracy of different pulse contour methods to measure CO compared to thermodilution CO measured with a PAC in major abdominal surgery patients.2. To assess the effect of propofol…
The objective of this new approach is: to reduce the number of conversionsfaster recoveryshorter hospital stay
To investigate the effect of Roux-en-Y gastric bypass on the rate and extent of absorption of metoprolol and its main active metabolite α-OH metoprolol, after a single oral dose of 95 mg metoprolol CR tablet in 10 female bariatric surgery patient…