188 results
We aim to confirm that Maastro endoluminal HDR contact brachytherapy boosting is feasible and may increase the chance of functional organ sparing of the rectum in patients with rectal cancer.
The aim of the study is to investigate whether SI-NETs can be visualized with indocyanine green (ICG) and near-infrared (NIR) fluorescence imaging (FLI).
The purpose of this research is to explore the needs of obesity patients and their partners or loved ones, to permanently change their lifestyle. These knowledge and insights can be used for new developments or to improve existing products/…
1. To assess safety of different doses of a single iv injection of SGM-1012. To assess the performance of SGM-101 in the intraoperative detection of colorectal or pancreas cancer by:a. Tumor-to-background ratio (TBR);b. Concordance between…
Primary ObjectivesTo assess the efficacy of 0.13mg/kg EMI-137 IV injection to detect lesions during colonoscopy, in subjects at high suspicion of developing colorectal cancer by:- Comparing the number of pathological lesions detected with WL with…
Primary: Feasibility of an in-house developed electromagnetic navigation system during real-time tumour tracking in rectal surgery.Secondary: Evaluation of the accuracy of the system. * Determine the accuracy of the navigation system relative to…
The goal of this pilot study is to calculate the sensitivity and specificity for discriminating tumour and benign tissues in vivo in colorectal cancer patients based on optical spectroscopy measurements. The secondary goal of this study is to…
To determine the kinetics of several immune cell subsets to evaluate the immune response to tissue damage and surgical manipulation caused by laparoscopic surgery. Additionally we aim to identify prognostic parameters for postoperative ileus, which…
The aim of this study is to determine feasibility of perineal reconstruction using a gluteal subcutaneous transposition flap (Luna flap) after eAPR for rectal cancer.
Primary objectives: To assess the feasibility, accuracy and safety of preoperative SPECT/CT and intraoperative fluorescence imaging after administration of 111In-labetuzumab-IRDye800CW in patients with PC of colorectal origin who will undergo…
This pilot study aims to report on the diagnostic value of indocyanine green and fluorescence laparoscopy on vascularization defects of the stomach and spleen during antireflux surgery.It is our hypothesis that many splenic and gastric infarctions…
This study is designed to explore the feasibility and added value of NIRF in minimally invasive esophagectomy and secondly to assess gastric conduit perfusion with intravenous injection of ICG.
Primary Objective: To assess the effect of bariatric and, eventually, subsequent body contouring surgery on appearance and HRQoL over time using the BODY-Q questionnaire. Secondary Objectives: The secondary objectives are (1) psychometric validation…
To assess the feasibility of real-time MRI temperature monitoring and ablation zone assessment during RFA of LAPC.
Our hypothesis is that treatment of peri-anal fistula with laser ablation is associated with equal closure rates compared to current therapies. As secundairy outcome, quality of life, postoperative pain and incontinence will be assessed. The primary…
The aim of this study is to investigate the amount of clinically relevant SRML (defined in this study as *5% muscle loss within one week measured by the cross sectional area (CSA) of the different muscles) in patients after major abdominal surgery…
Aim of the study is to develop an intraoperative technique for SLN mapping in colon cancer which is suitably in daily practice in colon surgery in an average hospital setting.
To assess PE rate and pouch characteristics in good and bad responders two years after LRYGB by MRI.
Primary objective:1. To investigate to what extent continuous vital sign monitoring can improve detection of adverse events in surgical ward patients as compared to current MEWS and nurse-worry assessmentSecondary objectives:2. To explore the…
To assess the safety and feasibility of HIPEC and CS in Western patients with peritoneal metastases of gastric cancer, in terms of morbidity and mortality. Secondary objective is to determine the effect on survival and recurrence.