16 results
To determine which advanced image enhanced modality is the most feasible for the detection of endometriosis lesions, with respect to the specificity and sensitivity of the investigated modalities. To determine which imaging modality reveals more…
To test an intra-operative fluorescent camera system with a fluorescent optical agent in detection of the sentinel lymph node. This will be compared to the standard method with radiocolloid and patent blue.
To test a near-infrared fluorescence camerasystem in order to detect folate-FITC in tumour tissue in women with ovarian cancer who undergo cytoreductive surgery.
1. Compare generic and pelvic-floor-specific QOL in patients who have been treated or gynaecologic cancer to that of patients without cancer attending a gynaecologist for pelvic floor symptoms.2. Examine how many and which patients receive or have…
SCAR study
Sonohysterographic evaluation of caesarean scar defects and determination of risk factors
Determination of the incidence of a scar defect .Determination of riskfactors for develpment of scar defects
1. To assess the feasibility of SLN identification in endometrial cancer.2. To examine in how many cases SLN biopsy provides results that will tailor adjuvant treatment3. To investigate if SLN biopsy in women with low- and intermediate-risk…
OBJECTIVE: through MRI research, we want to map the pelvic floor structures that are involved in holding a pessary in place
The primary objective of this study is to develop an diagnostic algorithm using ct-DNA, and TEPs as liquid biomarkers in combination with the existing ultrasound models (RMI and IOTA-models) and biomarkers (CA125 and HE4) to differentiate between…
Primary objective: To identify those groups of pregnant patients, planned to undergo cesarean delivery, who are at risk to develop severe hypotension (defined as a decrease of at least15% from the baseline tension) based on their preoperative volume…
Primary objective:To distinguish benign ovarium lesions from early cancer lesions, based upon their platelet RNA profile. Secondary objectives:* Evaluate the diagnostic accuracy of platelet RNA profiling in detecting early-stage ovarium cancer…
The primary objective is to assess the feasibility of intravenous injection of ICG to detect the border between healthy - and therefore fluorescent - bowel versus endometriosis.
Primary objective:- To assess the feasibility of a single intravenous injection of OTL38 in detecting endometriosis during surgery by determining the concordance between fluorescent signal and histopathological confirmed endometriotic tissue.- To…
To assess 1) the feasibility of in vivo measurement of biomechanical properties of the vaginal wall with the use of cutometry (Cutometer MPA 580 4mm) and indentometry (Indentometer IDM 800) and 2) the biomechanical properties of the vaginal wall.
Objective: Using near-infrared fluorescence (NIRF) with a Karl Storz® NIR fluorescence laparoscope to provide a real-time intra-operative enhanced visualization of endometriosis during diagnostic laparoscopy. Thus improving identification of…
An explorative study, that will include 15 patients and 15 volunteers without pelvic floor disorders, will be conducted to evaluate the possibilities of an open 0.25T MRI- system to assess the pelvic floor and to get a better understanding of the…
The main objective of this pilot study is to investigate the feasibility of fluorescence imaging with the fluorescence agent bevacizumab-800CW to detect endometriosis tissue.