19 results
The aim of this study is to determine novel (bio)markers that show a stronger correlation with signs of over- and under-treatment than the conventional adrenal steroid profile in children with CAH.
- assessment of age dependent reference values (ages 20 - 70 yrs) for plasma renin (activity and concentration), serum aldosterone and 24h urinary aldosterone (free and metabolites) during a regular diet and after a 3 day oral salt loading test-…
A core part of the scientific efforts of ENS@T researchers bases on the establishment of a common registry and associated collection of biomaterials. Patients with adrenal tumours prospectively included in the ENS@T registry will be asked to provide…
1. Examen if the outcome of the 1 mg Overnight Dexamethasone suppression test is influenced by the use of oral contraception.2. Examen how many weeks after ceasing the use of orale contraception the 1 mg Overnight Dexamethason suppression test is…
Comparison of the salivary cortisol response after a standardized exercise test between prepubertal heathy children and children with asthma.
The objective of the study is to determine whether 11C-metomidate PET can differentiate between BAH and APA./PAH
1 To evaluate the feasibility to measure cortisol levels in hair in healthy children and children with asthma who use inhaled corticosteroids2 To evaluate differences in cortisol levels in hair in healthy children and children with asthma who use…
The objective of the study is to determine whether it is necessary to take the blood pressure lowering medication (β-blocker, ACE-inhibitors or diuretics) of a patient into account prior to blood sampling for pheochromocytoma diagnostics. Therefore…
With a standardized approach in a population with difficult to treat hypertension we want to explore how frequenty PHA is a cause of hypertension and what the test characteristics of the aldosterone-renin ratio are. Additionally we want to…
To evaluate if a standardized running test will elicit an increase in salivary cortisol levels in healthy prepubertal children
In this pilot study we want to determine if a standardized cyclic ergometer test result sin a measurable and reproducible cortisol response.
To investigate cortisol and ACTH rhythm (frequency, amplitude and regularity of cortisol and ACTH secretory pulses) in patients with SCS and bilateral adrenal involvement.
To study the variability of the lateralisation of the aldosterone/cortisol ratio*s when 3 instead of 1 sample is obtained and to study whether instantaneous measurement of cortisol during the procedure will prove to be advantageous.
In this study we want to investigate long-term follow-up of patients with PA. The outcome will be analyzed based on whether a decision to treat was guided by CT/MRI or AVS or both.
Primary objective:a. How often do inhalation or nasal corticosteroids lead to suppression of the HPA- axis in HIV-treated patients? Secondary objectives:b. Are other variables associated with the HPA-axis suppression? c. Are cortisol measurements in…
This study has been transitioned to CTIS with ID 2024-513622-35-00 check the CTIS register for the current data. The primary objective of this study is to assess the number of detected pheochromocytoma lesions, proved by histology, with [18F]mFBG…
In this study we look at how long it takes for the levels of certain hormones and hormone-binding proteins to normalizediscontinuation of COC use, in particular corticosteroid-binding globulin.
This study has been transitioned to CTIS with ID 2024-512628-12-00 check the CTIS register for the current data. Primary objectives-To assess the concordance between [68Ga]Ga-PentixaFor PET/CT and AVS for identification and/or lateralization of APAs…
- To assure reproducibility of results reported by other groups to see whether the current SOP should be adjusted for local use in order to let the device be of value to future research projects of our department. - To confirm the ability to measure…