23 results
1. To investigate non-invasive 4D flow CMR for the assessment of aortic arch stenosis and compare and correlate this to conventional imaging modalities and to three-dimensional rotational angiography (3DRA) with computational fluid dynamics (CFD). 2…
Primary objectives: to investigate functional and histopathological changes of the right ventricle before and after PVR and PPVI. To investigate if non-invasive assessment of RV-remodeling using CMR T1 mapping and T1rho mapping is possible and to…
Cross-sectional study: To detect the normal range of amplitudes and segment intervals of the fECG. Case-cohort study: To compare the fECG between healthy fetuses and fetuses with various forms of severe CHD. To determine the diagnostic value of fECG…
To assess the accuracy and cost-effectiveness of PO screening for CCHD in the Dutch perinatal care system.
First objective: To assess late neonatal neurological outcome in infants with duct dependent CHD and to gain more insight into the timing of brain damage. We will determine whether the quality of GMs at an age of seven days and three months is…
To investigate whether it is feasible to perform a large national implementation study in which community based midwives in the Netherlands use a pulse oximeter for screening newborns for CHD.
Primary Objective:• Intracardiac blood total flow and maximum flow velocity measured by 4D MR, and compared with 2D MR.Secondary Objective(s):• Intracardiac pressures as assessed by 4D MR , compared with 2D MR, invasive catheterization and…
The primary objective of this study will be to investigate reproducibility of ROI-TDI for fetal cardial performance in a group of normal pregnancies, and compare this new proposed parameter with the Myocardial Performance Index. The data will be…
The current pilot-study will examine the relation between depressive symptoms and serum levels of pro-inflammatory cytokines in CHD-patients.
We will investigate the feasibility of using STIC technology to evaluate the normal fetal cardiac anatomy and morphology in different stages of gestation. Further we aim at making normograms of different intracardiac parameters in relation to…
To investigate the relation between characteristics of valve prosthesis on functional outcome andquality of life in adult patients with CHD. To investigate the prevalence and predictors of PPM in a population withCHD. To investigate the incidence of…
In this study we want to evaluate the clinical and diagnostic ability of the micro TEE transducer (7.5 - 5.5 mm diameter tip, 18.5 mm length tip with a 5.2 mm diameter shaft) (Figure 1,2), the smallest multiplane TEE in the world, in pediatric…
1- To investigate cardiac performance and clinical course after biventricular vs. univentricular repair in PA/IVS. 2- To correlate pre- operative RV and LV function with present RV and LV function. 3- To assess myocardial structural anomalies, which…
1. To investigate whether examination of STIC volumes give an investigator more information about the cardiac anomaly compared to 2D ultrasound.2. To evaluate the reproducibility of fetal heart examinations of STIC volumes by different investigators…
To compare feasibility, accuracy and intra-and interobserver variability of short-axis derived versus long-axis derived RV volumes by realtime 3D echocardiography.
To differentiate between gene expression in sepsis and sterile sirs.
Aim of the proposed study will be to investigate whether microvascular blood flow at baseline is impaired in Eisenmenger patients who experience symptoms of the *hyperviscosity syndrome*. Furthermore, in view of the controversy whether to perform…
- Create a protocol including work-up, treatment and follow-up of ACAOS- Give an overview of the current practices involving ALCAPA, ARCAPA and CAVF
We aim to study the patient specific threshold for arterial blood pressure to maintain adequate cerebral perfusion (CBFV) in the perioperative setting and the association between perioperative abnormalities with postoperative brain damage and…
To determine whether 4D-flow CMR volume measurements are superior to 2D-PC CMR volume measurements by comparing the intra-class correlation between 2D-PC flow CMR stroke volume measurements in the MPA and multi-slice volumetric RV flow volume to the…