124 results
The main objective of the single center, observational study is to assess the immediate and long term effects of TAVI on LVF and coronary flow by means of pressure volume loops, intracoronary flow assessment, echocardiography and cardiac MRI/CT.…
The objective is to collect additional data on the clinical outcomes (surgical data, safety and clinical performance) of the Medtronic Enable® Aortic Bioprosthesis in *real world* patients. The collected data will be used to improve aortic valve…
The main objective is to determine the early and late survival and reoperation outcome of VSARR in patients suffering from aortic root aneurysm with or without aortic regurgitation. Furthermore, we will evaluate the quality of using a SF-36 form.…
This study is aimed at evaluate whether the microTEE can be used in stead of the current TEE probe, or intracardiac ultrasound catheters (ICE) in adults with a structural heart disease. The aim of the study is to compare image quality, the workflow…
In this study we want to assess the structural THV integrity in situ and to identify the respective accommodation patterns of the different THV platforms and the interaction with the aortic root in situ.
The study objective is to evaluate the clinical outcome of percutaneous aortic valve implantation in consecutive *real world* patients with severe aortic valve stenosis intended to be treated with the Medtronic CoreValve System.
The primary objective of this clinical investigation is to assess the safety and effectiveness of the Perceval S-valve at 12 months after implantation when used to replace a diseased or dysfunctional aortic valve or aortic valve prosthesis. The…
The objectives of this study are to evaluate cardiac performance characteristics and adverse events rates associated with the EDWARDS INTUITY Valve in patients undergoing aortic valve replacement (AVR). The AVR surgical approach is either full or…
The main objective is to assess the effects of TAVI on cardiac sympathetic activity.
The purpose of this study is to assess the safety and device success of the Edwards CENTERA Transcatheter Heart Valve (THV) System in patients with symptomatic, severe aortic stenosis who are indicated for aortic valve replacement.
The objectives of this study are to:• To demonstrate the safety of the InSeal VCD implant. • To demonstrate the safety and functionality of the InSeal VCD delivery system in delivering and deploying of the InSeal VCD implant and withdrawal of the…
The main objective of the single center, observational study is to assess the immediate and long term effects of TAVI on biomarkers, correlated to clinical outcomes.
To evaluate the effects of MitraClip implantation on:* mitral inflow patterns during exercise* the atrial septum, moreover the persistence of the iatrogenic atrial septal defect and the consequential risk of right atrial and ventricular dilatation…
The objective of the study is to demonstrate the safety, feasibility and potential efficacy of using GDS Accucinch System in human subjects with heart failure and clinically significant functional mitral regurgitation.
To investigate whether the incidence of major thromboembolic complications is reduced with On-X compared to St. Jude medical.
Structural Integrity of the Medtronic Corevalve System after Transcatheter Aortic Valve Implantation
Knowledge about long-term structural integrity of the MCS may support the current trends to expand TAVI technology to lower risk patient populations with longer life expectancy.
To evaluate and compare complication and mortality rates tocurrent rates available for repairs with commercially availableannuloplasty rings. (0, 0+)
The main registry objective is to observe the safety and efficacy outcomes in patients where treatment of severe calcific degenerative aortic stenosis was intended with the commercially available Edwards SAPIEN* Valve.
The main objective of the single center, observational study is to assess the immediate and long term effects of PAVI on LVF and coronary flow by means of pressure volume loops, intracoronary flow assessment, echocardiography and cardiac MRI/CT.…
Our investigation aims at the translation of heart valve tissue engineering from the laboratory bench to clinical application. In the present study, we compare different cell sources in their ability to form heart valve tissue. Furthermore, as we…