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Cost-effectiveness of balancing stroke and bleeding risk using CHA2DS2-VASc in primary care patients with Atrial Fibrillation: a management study. CAFe

The objective of this study is to determine the effectiveness of the CHA2DS2-VASc prediction model as directive for the preventive management of AF patients in the first line.

Optimization of the hypothermia procedure in the ICU - the influence of bodycomposition on the succesful performance of therapeutic hypothermia

The purpose of this study is to do research what the effect of the BMI and fat percentage is on the speed of cooling.

Exploring the measurability of co-responsibility over time and in context, via design interventions

This study has a strong explorative and qualitative approach and set-up. Please note that the goal of the study is to further identify possible areas for innovation for professionals, patients and their partners. The aim for this study is NOT to…

Nervus X- Atrial Fibrillation trial (NX-AF)

The primary objective is to examine the impact of t-LLVS on electrophysiological properties of the atria and ventricles. Secondary objectives are:- to elucidate the correlation between proteostasis marker levels in serum and atrial tissue, and the…

DOAC Levels prior to Incision study: DALI study

To measure DOAC levels just before surgery of all DOAC patients in the LUMC with elective surgery for which ceasing of DOAC treatment is required.

Unravelling True buRden of atrIal fibrillation across then whole spectrUm; froM asymPtomatic pHase to critical disease.

Primary objective: To measure AF burden at population level.Secondary objective: Associate the AF burden with risk profiles in the general population.

Evaluation of the Feasibility of a Gamified Lifestyle Change Intervention for Patients with Atrial Fibrillation Scheduled for Catheter Ablation: GAMES4CARE.

The primary objective of this study is to evaluate the adherence to a 3-month gamification intervention integrated with a recently developed platform for continuous lifestyle monitoring (Care-On) in patients with AF referred for catheter ablation.…

Carotid Artery ImPlant for Trapping UpstReam Emboli
(CAPTURE) for Preventing Stroke in Atrial Fibrillation
Patients

To assess the safety, feasibility, and tolerability of the Vine* Embolic Protection System and implantation procedure in atrial fibrillation (AF) patients at high stroke risk who are unsuitable for oral anti-coagulants (OAC).

Reappraisal of Atrial Fibrillation: Interaction between HyperCoagulability, Electrical Remodeling, and Vascular Destabilisation in the Progression of AF - An observational exploratory study on pathophysiological mechanisms of AF progression AND on the role of LinQ/ CareLink guided patient tailored therapy in patients with AF (RACE V)

2.2 Primary ObjectiveTo study clinical factors, (blood) biomarkers and genetic markers related to AF progression in patients diagnosed with recent onset self-terminating AF with special reference to hypercoagulability.2.3 Secondary Objectives1. To…