258 results
To develop a prediction model for ICD-therapy in a study population of ICD and CRT-D patients using a multimodal dataset containing clinical and historical data from electronic health-records, remote monitoring-data, accelerometer-derived data and…
This current study aims to assess a patient specific therapy plan for patients with persistent AF by randomizing catheter versus thoracoscopic ablation for PV isolation without adjuvant substrate ablation in those patients. Subjects will be…
The aim of this study is to quantify and characterize the outcomes of radiofrequency (RF) ablation after, and the utility of electroanatomical mapping with the Advisor* HD Grid Mapping Catheter, Sensor Enabled* (hereafter called *HD Grid*) and…
The clinical study objective is to demonstrate the acute and 12 months safety and performance of the Cryterion Cardiac Cryoablation System when used as intended.
Patients with novel onset or recurrent atrial fibrillation have an altered myocardial sympathetic activity. The quantification of sympathetic activity with 123I-mIBG scintigraphy, as well as its change over time after restoration of sinus rhythm,…
To evaluate the efficacy and safety of stereotactic arrhythmia radiotherapy in patients with therapy refractory ventricular tachycardia.
The aim of this longitudinal study is to investigate the biological variation of haemostasis variables involved in thrombosis and bleeding in patients on long-term treatment with Dabigatran. This may enable us to provide recommendations for…
The aim of the proposed study is to evaluate atrial-specific K+-channels as new drug targets for the management of AF. Blockers of atrial specific K+-channels prolong repolarisation exclusively in the atria without proarrhythmic side-effects on the…
This study aims to evaluate the Corsano Cardiowatch 287-2 for heart rate, heart rate variability (RR intervals), oxygen saturation, respiratory rate, and blood pressure during strenuous activities such as High-Intensity Interval Training (HIIT).…
Demonstrate clinical safety and effectiveness of the Ablacath* Mapping Catheter and Ablamap® System in patients with paroxysmal (Redo only) or persistent or long-standing persistent AF. Phenotype patients and demonstrate the prognostication power of…
To evaluate the accuracy of catheter localization using the NorthStar software during real-time MRI-guided cardiac ablation therapy.
In this prospective interventional feasibility study, we would like to assess the feasibility of a home DC-ECV in the treatment of recurrent symptomatic AF performed by APP in 25 patients.
The VOLT CE Mark study will collect data to demonstrate that the Volt PFA System is functioning as intended in a clinical setting and to demonstrate acute safety and effectiveness for the treatment of symptomatic, recurrent paroxysmal atrial…
The objective of the clinical study is to evaluate the safety and efficacy of the Adagio Cryoablation System (iCLAS*) in the ablation treatment of persistent atrial fibrillation (PsAF). Data will be used to support a pre-market application (PMA).
Objective: To collect patient-reported symptoms, device data, and the clinical follow-up action of each remote transmission to develop an automated triage workflow that can discriminate between actionable and nonactionable evaluations. In addition,…
The main (primary) objective is to study the influence of sex on the pharmacokinetics (PK) of metoprolol in patients after CABG with heart valve surgery and patients with a STEMI/NSTEMI who are prescribed a standard dosage of metoprolol as part of…
The objective of this clinical trial is to demonstrate that ablation with the TactiFlex* SE Ablation Catheter, Sensor Enabled* (TactiFlex PFA), in conjunction with a compatible PFA and/or RF generator, is safe and effective for the treatment of…
The primary objective of this pilot study is to examine the impact of MNS on cardiac electrophysiology measured at a high-resolution scale during SR.
This study is designed to support the regulatory requirements for obtaining the CE mark for the Solia CSP S lead and to support post-market clinical follow-up requirements for the Amvia family (PMCF). Therefore the primary objective is to show…
The objective of the study is to demonstrate the safety and feasibility of the Adagio Cryoablation System in subjects with Atrial Flutter (AFL).