308 results
In patients with NSTEMI we aim to: 1) compare coronary vulnerable plaque detection between 18F-NaF-PET-CMR and invasive coronary angiography, 2) investigate the relation of coronary vulnerable plaques using 18F-NaF-PET with myocardial infarction…
To investigate the association between shear stress and plaque growth and plaque composition changes over time. Furthermore, it will be investigated how these plaque changes influence the local wall stress.
The primary objective of this study is to demonstrate the clinical performance of PRO-Kinetic Energy stent in subjects with atherosclerotic disease of native coronary arteries.
This study aims at establishing the influence of sampling site on the variability of ACT measurement at the end of coronary angiography or PCI.
Describe the relation between patterns in biomarkers of vascular inflammation, plaque instability and hypercoagulability and the incidence of recurrent ACS
In the present study we aim to determine the value of microvascular resistance measurements in the acute setting to predict the occurrence of MVO in the following days, using the combined pressure-flow wire. Therefore patients with an acute MI will…
The purpose of this trial is to evaluate the safety and effectiveness of the NovaCross* micro-catheter when used to facilitate crossing of Chronic Total Occlusion (CTO) lesions in coronary arteries. The procedure will be conducted on consenting…
Evaluate clinical performances of Cre8 in *all comer* population
To answer the following research questions: 1. Do intimal arterial calcification and medial arterial calcification in the lower extremity arteries increase the occurrence of cardiovascular disease in people with a high risk of cardiovascular disease…
Determining the role and influence of genetics, their polymorphisms and immunologic phenotype in arteriogenesis in patients with obstructive coronary artery disease (CAD).
To determine whether CCTA can provide a more efficient diagnostic work-up in suspected NSTE-ACS patients with an initial inconclusive work-up by identifying patients that do not have significant coronary artery disease.
Primary Objective: The objectives of this study are to assess lumen, scaffold, vessel dimension, malapposition and tissue coverage as assessed by quantitative angiography, intravascular optical coherence tomography and intravascular ultrasound…
The objective is to study the feasibility of different PET tracers to detect vulnerable plaques in patients with a recent acute coronary syndrome and co-localize these inflammatory lesions with anatomical plaque features obtained with CT based…
Primary Objective:- To assess lipid levels of STEMI patients over a long course. Secondary Objectives:- To assess the association between poorly controlled cholesterol and (apo) lipoprotein levels for the long term outcome in STEMI patients.- To…
To determine the added value of signs, symptoms and H-FABP measurement in in- or excluding acute coronary syndrome in patients with thoracic complaints in general practice
Primary Objective: • To study the accuracy of a combined CT angiography and DECT for complete imaging of CAD compared to the reference standard, ICA and SPECT MPI. Secondary Objective(s): • To compare DECT analysis in the detection of perfusion…
Primary Objective:* Assess the safety and performance of the MeRes100 Sirolimus Eluting Bioresorbable Vascular Scaffold System (BRS) in subjects with de novo native coronary artery lesions as indicated by proportion of population reporting with…
The aim of this study is to investigate whether iFR-measurement of non-infarct related arteries during the acute phase of STEMI is in agreement with iFR and FFR measurement at the staged procedure.
1) To evaluate changes in microvascular resistance of the infarcted area in the first hours after ST-elevation myocardial infarction and during the recovery period (<5 days)2) To classify patients according to recovery of microvascular…
To compare the image quality, visibility of perfusion deficits and myocardial blood flow of a conventional analog PET system with a digital PET system in 30 patient referred for PET myocardial perfusion imaging (MPI).