16 results
This pilot study compares two existing techniques to see if there's a differt in donor blood consumption.
The main objective of the study is to investigate whether of the biolimus eluting and biodegradable polymer NOBORI* stent is non-inferior or even superior to the everolimus eluting XIENCE-V/XIENCE-PRime/PROMUS* stent in daily practice.
The main objective of the study is a head tot head comparison of the everolimus coated XIENCE-V* stent with the paclitaxel coated TAXUS* stent in order to observe whether there is a difference in clinical outcome between both stents. Efficacy of…
The main objective of the present study is to investigate whether the ORSIRO coronary stent is non-inferior compared to the Xience coronary stent in patients with total coronary occlusions.
· Explore the relative impacts of iodine concentration versus iodine delivery rate on intra-coronary attenuation. · Describe the effect of iodine concentration on contrast bolus characteristics e.g. bolus homogeneity, time-to-peak, and pressure…
Does a low protamine-to-heparin ratio lead to a reduction in postoperative blood loss and improved postoperative hemostasis when compared to a high protamine-to-heparin ratio in cardiothoracic surgery?
This study will evaluate if the use of a mini extracorporeal circuit is an improvement for the patient. The study investigates how much the use of a mini extracorporeal circuit will change the homologous blood requirements and the magnitude of the…
1.) First, we hypothesize that a reduction of myocardial damage explained by lower levels of myocardial damage markers (e.g. troponin I, CK-MB) by sevoflurane may be related to a reduction of inflammatory mediators (i.e. TNF-α, CD11b/CD18 cells, and…
The purpose of this project is to explore whether a short treatment with dipyridamole (2.5 days; i.e. 5 capsules) can reduce ischemia-reperfusion injury in the forearm.
The aim of this study is to evaluate cardio-protective effects of xenon inhalation in humans and to identify enzymes contributing to cardio-protection influenced by xenon in patients scheduled for CABG surgery.
The aim of this study is to evaluate the immediate effect of xenon inhalation on cardiac performance in patients scheduled for CABG surgery in comparison with the effect induced by sevoflurane inhalation.
Is targeting an ACT > 400 seconds equivalent compared to an ACT > 480 seconds with respect to PRBC transfusion rates during hospitalization in patients undergoing cardiac surgery with cardiopulmonary bypass?
This PIONEER IV trial aims to demonstrate a non-inferiority of QFR-guidance PCI to usual care PCIwith respect to Patient oriented Composite Endpoint (PoCE) at 1 year with the unrestricted use ofHT Supreme-SES in an all-comers population (including…
The here proposed randomized clinical trial, named *POStoperative INTELLiVENT-adaptive support VEntilation in cardiac surgery patients II* (POSITiVE II), compares INTELLiVENT-ASV with conventional ventilation in patients planned for elective cardiac…
This protocol will provide data to comply with regulatory requirements as well as gain substantial additional information on patients in a real world setting. This protocol will compare clinical outcomes of the MISTENT and XIENCE in a broad patient…
This protocol will compare clinical outcomes of the SUPRAFLEX and XIENCE drug-eluting stents in a broad patient and lesion population and will gain substantial additional information on patients in a real world setting. These data will also provide…