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Lipohypertrophy and endermotherapy®
Effect of endermotherapy® treatment in insulin induced lipohypertrophy in type 1 and 2 Diabetes Mellitus patients.

Primary objective;Change in section and extent of treated LH after treatment with endermotherapy® and without treatment. Change in resistance and pain during injection at the right and left LH and changes in appearance aspects of LH right and left.…

efficacy of barrier cream with or without Honeyin intergtrigo

Correcting the causative factors of intertrigo is critical. Take steps to eliminate friction, heat, and maceration by keeping folds cool and dry. The goals of pharmacotherapy for intertrigo are to reduce morbidity and to prevent complications. To…

An independent prospective randomised controlled trial comparing the efficacy and cost effectiveness of infliximab and etanercept in 'high need' patients with moderate to severe chronic plaque type psoriasis

What is the incremental cost effectiveness ratio of the use of etanercept versus infliximab?Are there subgroups of which infliximab or etanercept is more or less cost-effective in daily practice?Primary objectives: 1. To compare clinical efficacy of…

Doxycycline versus minocycline in the treatment of rosacea: a randomized controlled trial.

To compare the efficacy of doxycycline 40 mg (Efracea) versus minocycline 100 mg treatment in adult patients with papulopustular rosacea.

Fractional laser as treatment option for various pigment disorders

The primary objective of this study is to assess the efficacy and safety of non ablative and ablative fractional lasers in various pigment disorders.

European multi centre trial to compare the effectiveness of two different phototherapy narrow band UVB protocols in vitiligo

The primary objective of this study is to compare the effectiveness of two different phototherapy protocols (continuous treatment for 6 months, or 2 continuous treatments for 2 months separated by one month interruption (2-1-2-1), with a total…

NB-UVB phototherapy versus Excimerlaser after minigrafting in vitiligo patients

The objective of this study is to evaluate the clinical effects (start and grade of repigmentation) of NB-UVB versus 308-nm Excimer lasertherapy on pigment spread after minigrafting in vitiligo patients.

A 24 week multinational multi-center study consisting of a 12-week single blind study to evaluate the efficacy and safety of methotrexate versus azathioprine treatment in adult patients with chronic severe atopic dermatitis and a 12-week follow up period.

To compare the efficacy and safety of methotrexate versus azathioprine treatment in adult patients with chronic severe AD.

Optimizing the treatment of psoriasis with methotrexate; after 40 years the first dose-finding study.

Our aim is to optimize treatment for patients with moderate to severe psoriasis by creating evidence for the optimal dose of MTX (on short- and long-term) with the largest disease reduction and the least side effects.

A single (assessor) blinded, randomized, parallel-group, monotherapy trial to evaluate the pharmacokinetics and safety of tralokinumab in children (age 6 to <12 years) with moderate to-severe atopic dermatitis.

Primary objective: To establish the PK profile after multiple SC administrations of tralokinumab in children with moderate-to-severe AD.Secondairy objectives: - To assess the safety and tolerability of multiple SC administrations of tralokinumab in…

A preliminary study on the effect of photothermal laser therapy on the vascularization and innervation of psoriatic lesions*

This project aims to assess the effect of laser therapy on the blood vessels and (peripheral) innervation of psoriasis plaques. The primary objective is to quantify the regression and recovery of nerves compared to blood vessels. We hypothesize that…