31 results
To measure intraprostatic concentrations and serum levels of fosfomycine after a single oral or intravenous dose prior to TURP. This is done to achieve more insight in whether fosfomycin is a suitable antibiotic to use as profylaxis or treatment of…
Primary Objective: Assess the incidence of wound infections in patients treated with venous stenting and AV fistula and Prevena negative pressure wound therapy (NPWT).Secondary Objective(s): Assess the incidence of lymph leakage in patients treated…
To estimate the risk of Q fever infection in children and adolescents in various exposure groups, estimate the true regional incidence of Q fever infections in children and adolescents, identify associated risk factors, and assess the impact of Q…
The main purpose of this study is to determine the appropriate age (10, 12 or 15 years) for a second MenC conjugate (MenCC) vaccine immunization in Dutch children that received a primary MenCC vaccination at a young age. A conclusion will be based…
To compare the number of responders to vaccination with pneumococcal and conjugated Hib vaccine at different time points after last dose of rituximab, to investigate what the ideal moment of vaccination would be. Secondly to study the immune-…
Primary Objective: *To evaluate the immune responses 1 month after 3 doses of 13vPnC as measured by fold rises of serotype-specific immunoglobulin G (IgG) geometric mean concentrations (GMCs) in subjects *2 years of age. Secondary Objectives: *To…
Primary objective: The primary objective of the study is to determine the effect of concentration/meditation on the innate immune response induced by a lipopolysaccharide (LPS) challenge. Secondary Objective(s): There are two secondary objectives:1…
Primary Objective: The primary objective of our study was to prospectively study the fecal acquisition of NDM-1 carbapenemases producing Enterobacteriaceae during foreign travel and the persistence rate of acquired NDM-1 carbapenemases producing…
To identify complement donors with no or low antibodies to Meningococcal strains to be used used as a complement source in SBAs against a panel of meningococci during evaluation of clinical trial samples
The aim of this study is to analyze the effect of full-mouth tooth extraction on the oral microflora, using both culturing and PCR techniques.
I. Evaluation of the nature and maintenance of specific cellular immune mechanisms after infection with Bordetella pertussis in different age groups, to identify critical parameters for pertussis re-emergenceII. To relate individual patient*s…
Primary objective is to investigate if donor feces infusion is effective in eradication of ESBL producing Enterobacteriaceae in the large intestine. Secondary objective is to determine whether ESBL decolonisation of the large intestine actually…
To compare splenic function between patients who received splenectomy and patients treated with embolisation. Furthermore, splenic function between patients with different types of embolisation (proximal versus distal) will be compared
1) To test the feasibility of vaccinating pregnant women against B. pertussis in preventing B. pertussis infection in newborn babies.2) To test the safety of vaccinating pregnant women against B. pertussis in preventing B. pertussis infection in…
Objective: to study host and pathogen determinants of S. aureus infection to identify a putative antigen as target for the development of a prophylactic vaccine against S. aureus.
Objective: 1) to assess whether adequate serum and interstitial fluid levels of cefazolin are reached during surgery in obese and non-obese patients, 2) to develop a population pharmacokinetic model for cefazolin which allows the characterization of…
To study the immune response to vaccination with influenza virus vaccine, conjugated Hib and pneumococcal vaccine after treatment with rituximab in association with the reconstitution of immune function (in terms of amount of B-cells and…
In this study we want to study:1) what is the prevalence of CA-MRSA asymptomatic carriership among MSM policlinic visitors?2) What are risk factors for CA-MRSA carriership and/or infections among MSM?3) Is CA-MRSA among MSM transmitted through…
Determine asymptomatic nasopharyngeal pneumococcal carriage and serotype distribution in elderly aged 65-70 years, 71-80 years ald 80 years and older. Assessment of the value of PCR compared with conventional culture methods.
The aim of this study is to analyze the long-term effect of full-mouth tooth extraction on the oral microflora, using the 16S next-generation sequencing technique.