41 results
Main objective: investigate the correlation between CAP-values with fat percentages found at 1H-MR Spectroscopy and steatosis grade at liver biopsy. Secondary objectives: investigate the reproducibility of CAP-measurements; investigate the…
To compare accumulation of liver fat (as measured using CAP) and liver fibrosis (as measured using fibroscan) between patients with quiescent and active inflammatory bowel disease
To investigate the correlation between the CAP-value measured with the FibroScan® device and liver fat percentage measured with 1H-MRS in a well-characterized cohort of obese children at risk of having fatty liver disease.
main objective: Investigate the prevalence of liver fibrosis according to TE values in children enrolled in a HPN-program. Secondary objectives: Investigate the correlation between TE values and ELF test score and APRI in children enrolled in a HPN-…
The aim of this study is to compare the image quality, diagnostic confidence and patient discomfort when using either positive (50 ml Télébrix Gastro + 950 ml water ) or negative 1000 ml water only in outpatients undergoing a contrast-enhanced…
Investigate whether *T1-mapping of the liver with the liver specific MRI contrast agent Gd-EOB-DTPA allows measurement of the change in liver function after ERCP treatment of a dominant stricture in PSC patients.
This study aims to collect biochemical evidence for the pro-hemostatic capacity of DDAVP in patients with cirrhosis, in order to proceed towards a more rational clinical use of this drug.
The aim of this study is to retrieve extra measurements by Nexfin and laboratory testing in the per- and postoperative period. Can the use of Nexfin contribute in the generation of meaningful data to get an idea of the hemodynamic state of the…
The purpose of this study is to improve the diagnosis and management of hepatocellular adenoma.
Primary:- To determine default values of liver phosphorus metabolite ratios using 31P-MRS at 3.0T in healthy volunteers- To determine default values of fractional anisotropy (FA) and apparent diffusion coefficient (ADC) in the liver using DTI-MRI at…
Main goal: In this non-invasive pilot study, we want to investigate whether these techniques can discriminate between healthy livers and livers with cirrhosis. For the new techniques to be applied as an alternative for biopsy, the output values of…
To calculate the repeatability and reproducibility of MRE stiffness measurements in the liver on a voxel-by-voxel basis.
To assess the diagnostic accuracy of MR Elastography in detecting and monitoring different degrees of liver fibrosis compared to FibroScan and histopathology in patients with suspected chronic viral liver disease and non-alcoholic fatty liver…
Primary Objective: * The feasibility of combining MRE and 1H-MRS in NAFLD to distinguish simple steatosis from NASH. Secondary Objective(s): * The influence of steatosis on MRE measurement* The influence of inflammation on MRE measurement
To study the effect of peginterferon alpha and ribavirin on spermatozoa
Validation and quantification of 3.0 Tesla 1H *MRS for the assessment of hepatic steatosis in patients with non alcoholic fatty liver disease and patients chronically infected with hepatitis C. Is there a close correlation between the 1H *MRS…
Primary Objective:Validate the accuracy of:· MR Flow mapping in measuring PPG in patients with GoreTex®-covered TIPS as compared to the gold standard, portography.· MRA for establishing TIPS patency as compared to Doppler US and using invasive…
To establish platelet function during orthotopic liver transplantation.
The aim of this study is to validate a protocol for ultrasonographic hepatic fat assessment, by means of Magnetic Resonance Imaging technique (MRI) as gold standard.
Validation of pre-operative H1-MRS at 3.0 Tesla for assessment of hepatic steatosis as a risk factor for postoperative morbidity and mortality after hepatectomy. Is there a close correlation between the 1H -MRS measurement of fat and the…