861 results
To establish the safety and preliminary efficacy of Check-Cap*s P1 Capsule System in patients eligible for CRC screening
usefulness of I-FABP in the surgical managment of small bowel obstruction caused by adhesions.
The objective of this explorative study is to assess the value of anatomical and functional magnetic resonance imaging (MRI) and 18F-fluorodeoxyglucose positron emission tomography and computed tomography (PET-CT) in the evaluation of treatment…
The primary study objectives are as follows:-To evaluate the pharmacokinetics (PK) of golimumab in pediatric subjects aged 2 through 17 years with moderately to severely active UC.-To evaluate the safety of golimumab in pediatric subjects aged 2…
To compare the percentage of incompletely resected polyps during colonoscopy for polyps sized 1-4 mm, 5-9 or 10-20 mm.
Determining the feasibility and diagnostic accuracy in terms of sensitivity and specificity of intraoperative detection of peritoneal carcinomatosis of colorectal origin by intraoperative fluorescence imaging using the VEGF-targeting optical imaging…
The primary objective of this study is to determine the sensitivity of the fluorescent tracer bevacizumab-IRDye800CW using a NIR fluorescence endoscope ans spectroscopy probe in identifying adenomatous polyps during surveillance endoscopy in…
Determine the existence of a relation between GER and apnea and their underlying mechanisms, in infants *37 weeks * 12 months.
The aim of this present diagnostic study is to determine the accuracy by which we can detect residual disease after neoadjuvant chemoradiotherapy.
To demonstrate that the infliximab serum concentration of Remsima* is non-inferior to the infliximab serum concentration of Remicade , 16 weeks after switch from Remicade to Remsima* in subjects with CD, UC or RA in stable remission for > 30…
To determine the correlation between concetrations of inflextra/ infliximab as measured using finger prick blood and lateral-flow assay and using venous blood and the standard sanquin ELISA.
Currently, only few publications exist which describe MRI for esophageal cancer. Therefore, the objective of the study is to develop a MRI protocol for imaging of this organ. The research will particularly be focussed on functional MRI. Those scans…
Determination of microbiological, macro and microscopic / histological characteristics after RYGB, mainly targeted at identifying inflammatory characteristics, bacterial (over) growth and / or atrophy / metaplasia in the excluded stomach and the…
The first objective is to assess the value of colonoscopy screening in HL survivors. The second objectives are to evaluate the neoplasia characteristics and its relation to radiotherapy and chemotherapy, in order to improve the understanding of the…
Primary Objective:* To evaluate the long-term safety and tolerability of MT-1303 in subjects with moderate to severe active CDSecondary Objectives:* To evaluate the long-term effects of MT-1303 on clinical outcomes in subjects with moderate to…
To investigate feasibility, safety and toxicity as well as immune-response of an allogeneic tumor cell lysate (PheraLys) loaded onto autologous dendritic cells (MesoPher) in resected pancreatic cancer patients who received adjuvant standard of care…
This is a prospective phase II non-randomized single-center study in patients with LAPC. Patients are first treated with up to 8 cycles of FOLFIRINOX, followed by stereotactic radiotherapy for a total dose of 40 Gy in 5 fractions. Due to the known…
Primary Objective: Visualization and quantification of tumor hypoxia with [18F] HX4 PET imagingSecondary Objectives: - Correlation of [18F] HX4 with local tumor recurrence and survival- Correlation of hypoxia imaging with blood hypoxia markers -…
The primary objective of this study is to evaluate the long-term safety and tolerability of orally administered telotristat etiprate.The secondary objective is to evaluate changes in patients* quality of life (QOL) through week 84.
* To determine the minimum effective dose of 5-aminolevulinic acid (Gliolan) for adequate MitoPO2 measurements during upper endoscopy.