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Colonic motility distal to a deviating ileostomy after rectal resection and construction of a primary anastomosis

The primary aim is to study colon motility following rectal resection with the construction of a deviating ileostomy in patients that received an enema as bowel preparation. We hypothesise that CTT is halted or decreased, similar as in patients that…

Perianal and anorectal complications in patients with inflammatory bowel disease in time

1.To prospectively evaluate the course of anorectal function in IBD patients with perianal lesions2.To establish potential biomarkers to predict the course of anorectal function in IBD patients with perianal lesions

Anorectal function and clinical symptoms in patients with a third degree anal sphincter rupture: longterm follow-up

- to establish the long-term alteration of anorectal function in women after promary repair of a third degree obstetrical anal sphincter rupture- to evalute the following complaints in women in late postpartum period after 3rd degree rupture:…

Simultaneous Integrated Boost Radiation Therapy with concomitant Capecitabine and Mitomycin-C chemotherapy for locally advanced Anal Carcinoma

Primary objective of the study is the assessment of the dose limiting toxicity (DLT) and the maximal tolerated dose (MTD) of capecitabine and mitomycin-C with concomitant SIBRT in patients with locally advanced anal carcinoma.Secondary objectives…

CyTOF and microbiota analysis on Crohn*s disease-associated and idiopathic perianal fistulas

To determine the differences in immune cell populations, microbiota and fibroblasts between fistulas from patients with and without Crohn*s disease.