286 results
To determine whether surgery induces changes in the liver vasculature of patients with colorectal cancer.
To identify circulating mediators that are released after surgery and which are responsible for macrophage activation.
The objective of this new approach is: to reduce the number of conversionsfaster recoveryshorter hospital stay
In this study, we first intend to investigate the optimal time point for measurement of hypoxia in esophageal, pancreatic and rectal cancer using 18F-HX4-PET and then assess reproducibility of hypoxia measurements in these tumor types.
Determine normal ADC values and the reproducibility of the ADC values in normal liver tissue and colorectal liver metastases in a multicentre trial. Determine the effect of lesion volume on reproducibility of the ADC values.
In patients undergoing surveillance endoscopy for Barrett;s oesophagus or work-up and treatment for early neoplasia in Barrett's oesophagus we will evaluate the N-Vision pVLE system for the following items:1) feasibility of the system2) the…
This clinical trial will evaluate the inter-observer agreement of a simple, consensus driven NBI classification system of surface patterns and its ability to differentiate dysplastic vs. non-dysplastic BE in patients undergoing BE screening or…
To assess the usefulness of NBI in the visualisation of PVs in Western BE patients (in this study using the new Excera III NBI-system), to investigate the discordance between the Japanese and Western definition of de distal end of the Barrett*s…
The study aims to determine the safety and efficacy of the steering module in a clinical setting.
Primary: To provide metastatic colorectal cancer patients with access to aflibercept and todocument the overall safety in these patientsSecondary: To document the Health-Related Quality of Life of aflibercept in this patientpopulation
The aim of this study is to answer the question if RFA is an effective treatment modality in the long term, for patients with Barrett's esophagus containing HGIN or EC.
To identify relevant geriatric assesment tests to develop a clinical instrument for predicting tolerance defined as the change of developing a complication in elderly patients (>=70 years) with a coloncarcinoma that recieve surgical treatment…
To evaluate the efficacy of Enterocutaneous fistula ( ECF) repair using the Biodesign enterocutaneous fistula plug ( Cook Medical).The primary objective of this study is to determine the feasibility, tolerance and primary technical success rate of…
The objective of this pilot study is to investigate wether:- Increased Hb levels prior to the operation can prevent blood transfusions preoperative, blood transfusions have a negative effect on the survival of cancer patients- Treatment with…
Primary objective: to investigate the intra- and interfraction motility of the CTV (the primary tumor as well as any affected celiac lymph nodes) in radiotherapy for esophageal cancer, and to determine adequate CTV-ITV margins.Secondary objective:…
To assess whether a decrease in heart volume is accompanied by changes in myocardial strain, strain rate, inferior vena cava diameter and blood levels of NT-proBNP and troponins.
The aim of this study is to investigate the feasibility of VLE to detect the presence of glandular structures under the NSE after RFA and direct correlation of VLE images with histopathology.
The aim of this phase-2-study is to assess the feasibility of surgery following CRT in patients with cT4 oesophageal carcinoma with regard to morbidity, mortality and the possibility to achieve a R0 resection.
The primary objective is the safety and feasibility of CEA/frameshift derived neopeptide loaded DC in patient with MSI-positive colorectal cancer and persons who are known to be carrier of a germline MMR-gene mutation with no signs of disease yet.…
Prospective study: The potential use of intraoperative, ICG based, fluorescence imaging of LN's during CRC lymphadenectomy.