59 results
The aim is to investigate the feasibility of DBS from finger prick for measuring infliximab drug levels and ATIs compared with the results of venepuncture serum sample measurements. As a secondary objective, measurements of albumin and CRP will also…
To determine the correlation between concetrations of inflextra/ infliximab as measured using finger prick blood and lateral-flow assay and using venous blood and the standard sanquin ELISA.
To compare accumulation of liver fat (as measured using CAP) and liver fibrosis (as measured using fibroscan) between patients with quiescent and active inflammatory bowel disease
ObjectiveTo identify biomarkers for CAL in drain fluid and serum, in addition to RT-PCR for E. faecalis, that increase specificity and positive predictive value.
The main goal of this pilot study is to test feasibility of the present commercially available near-infrared fluorescence cholangiography (NIRFC) laparoscopic device during the laparoscopic cholecystectomy.
The overall objectives of this proposal are to develop two indices capable of measuring intestinal damage, and, separately, inflammatory disease activity in Pediatric Crohn's disease by means of Magnetic Resonance Imaging with Enterography…
Primary objective:Pharmacokinetics/-dynamics of 124I-F8IL10 Secondary objective:Dosimetric parameters of arthritic joints and internal organs.
The overall aim of this study is to assess the feasibility of implementing MRE for use in evaluating fibrosis in patients with Crohn*s Disease (CD) in a multicenter setting.The primary objective for this study is to evaluate *gain of enhancement* as…
The aim of the study is to gain more insight in the course of intestinal oxygenation, urinary I-FABP concentration, and plasma Citrulline levels (as markers for intestinal damage and recovery) after NEC in relation to time to full enteral feeding…
The primary objective is the determination of faecal reference values of calprotectin, elastase and alpha-1-antitrypsin after RYGBP.
To study MRI of the small bowel and colon in determining disease activity in patients with Crohn*s disease.
Study the very long-term efficacy (regarding reflux control) of antireflux surgery in children with severe GERD.
The primary objective is to assess the feasibility and accuracy of dynamic contrast enhanced MRI in diagnosing UC or CD in children as compared to endoscopy and abdominal ultrasound.The secondary objective is to assess the feasibility of dynamic…
In this study we will explore the examination with the second generation Pillcam capsule (PCCE 2) in patients with Crohn's disease. Crohn's patients with symptomps that need an endoscopy according to the treating physisian, will be asked…
Aim of this prospective study is to determine (temporal changes in) the intestinal microbiota in faecal specimens and microbiota adhering to the intestinal mucosa using bacterial DNA-based profiling methods.
The main objective is to validate WBC scintigraphy as a sensitive tool to measure and quantify inflammatory load in different severities of UC.The secondary objectives are to explore whether other disease activity markers, like serum C-reactive…
Early detecting of dysplasia and adenocarcinoma in patients with long excisting crohn's disease.
The aim of the study is to quantify the accuracy and cost-effectiveness of a diagnostic decision rule for OBD, in patients with persisting lower gastro-intestinal complaints in primary care.
1. Determine the presence of lesions in the upper gastrointestinal tract in patients with a primary diagnosis of CD and UC, using endoscopy and histology, before starting medication.2. Asses the prevalence of histological lesions such as focal…
To assess the (additional) diagnostic value of faecal calprotectin in children, age 4-18 years, with symptoms suggestive for IBD, in a primary and secondary/tertiary care setting.