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A Multicenter randomized trial, comparing a 25G EUS Fine Needle Aspiration (FNA) device with a 20G EUS ProCore Fine Needle Biopsy (FNB) device

To compare the performance and diagnostic accuracy of two EUS-guided tissue acquisition devices; a 25G Echotip Ultra Fine Needle Aspiration (FNA) device and a new, more flexible, 20G Echotip ProCore Fine Needle Biopsy (FNB) device.

MAL-PDT of superficial basal cell carcinoma using two light fractions with one or two hours interval: comparison of illumination at 3 and 4 hours with illumination at 3 and 5 hours after application of MAL

The aim of the present study is to study Metvix® photodynamic therapy (MAL-PDT) of superficial basal cell carcinoma (sBCC) using two light fractions with one or two hours interval: comparison of illumination at 3 (20 J/cm2) and 4 hours (55 J/cm2)…

A feasibility study comparing two strategies of oral contrast in patients undergoing contrast-enhanced abdominal CT: 50 ml Télébrix Gastro + 950 ml water vs 1000 ml water only.

The aim of this study is to compare the image quality, diagnostic confidence and patient discomfort when using either positive (50 ml Télébrix Gastro + 950 ml water ) or negative 1000 ml water only in outpatients undergoing a contrast-enhanced…

The BIOPRES-trial; Transrectal Biopsies of the Prostate: End versus Side firing

To investigate the difference between side and end-firing in transrectal prostate needle biopsies in terms of qualitative and quantitative prostate cancer detection.

Three non-invasive Treatment Options for superficial basal cell carcinoma:
PDT vs. imiquimod vs. 5-fluorouracil

This research has the goal to determine which treatment is the most effective treatment in terms of prevention of treatment failure, in costs and has the patients preference when comparing PDT, Imiquimod and 5FU.

"The Shrink Study: shrink factor of resected tumour mucosa in patients with oral squamous cell carcinoma"

Investigate whether different resection modalities such as MO or TL cause a different amount of shrinkage in the mucosal margins of resected OSCCs.

Topical Ingenol mebutate versus 5% 5-fluorouracil versus 5% Imiquimod versus photodynamic therapy in treatment of actinic keratosis: a multi-center randomized efficacy and cost-effectiveness study

Determine which treatment is the most effective treatment in terms of lesion reduction, costs and patient satisfaction when comparing topical treatment with photodynamic therapy (PDT), 5% 5-fluorouracil (5-FU) cream, 5% Imiquimod (IMI) cream and…

Assessing optimal treatment settings for the ablation of locally advanced pancreatic cancer with CT-guided percutaneous irreversible electroporation: a randomized feasibility study.

The objective of this study is to compare two IRE protocols for the treatment of LAPC that are currently being used in clinical treatment, to allow for the determination (based on survival and co-morbidity) of the optimal treatment protocol for IRE…

Treatment of superficial basal cell carcinoma by topical photodynamic therapy with fractionated 5-aminolevulinic acid 20% versus two stage topical photodynamic therapy with methylaminolevulinate

To compare effectiveness, costs and patient preferences in the treatment of sBCC with fractionated 5-ALA 20% PDT versus MAL PDT in 2 sessions.

FREE study: investigating the effectiveness of EMDR as a treatment for Fear of Cancer Recurrence among cancer survivors.

The aim of the present study is to investigate the effectiveness of EMDR on FCR in breast and colon cancer survivors who have high levels of FCR at baseline. The effect on post-traumatic stress symptoms, quality of life, and physical symptoms will…