104 results
The principal objective of the study is to determine if the performance of the new technique (magnetic tracer and magnetometer) is equivalent to the performance of the standard technique (patent blue dye and radioisotope, wire localization).The…
The aim of this pilot-study is to examine the accuracy of MRL compared to current nodal staging methods. We expect anacceptable accuracy of the MRL based on earlier studies with gadofosveset enhanced MRI in rectum cancer patients. Then the MRL could…
The primary objective (on lesion-based analysis) is to show that pre-treatment 89Zr-trastuzumab PET/CT is able to select lesions not responding morphologically from treatment with T-DM1 (applying RECIST 1.0 criteria)Secondary Objectives and…
Our study aim is to assess whether MARIA* can provide diagnostic information that can supplement, and in some cases, replace mammography as a tool in the symptomatic workflow. We will also seek patient feedback on this non-ionising, non-compressing…
The main objective of this study is to improve the power of breast ultrasound examinations by evaluating tissue alterations by means of Elastography. Recent studies have shown that there is a correlation between stiffness and malignancy of tissue.…
To determine the concordance between the ex vivo anthracycline sensitivity test and in vivo response to anthracycline-based NAC. Also, optimal cut-off values for the ex vivo anthracycline sensitivity assay are determined to carefully predict in vivo…
To discriminate the acquired anti-hormonal resistance phenotypes in patients based on ER expression levels by FES-PET in order to select patients eligible for estrogen therapy.
The objective of our study is to to assess the diagnostic performance of 7T CE breast MRI in comparison to the current clinical standard of 3T MRI and histopathology on a intra-individual basis.
The principal objective of the study is to determine if the performance of the new technique (magnetic tracer and magnetometer) is equivalent to the performance of the standard technique (patent blue dye and radioisotope; or radioisotope alone).The…
Is ductoscopy with white light and autofluorescent light a useful method for diagnosing precancerous breast lesions?
The primary objective is to assess the contribution of HER2-PET to subsequent anti-HER2-therapy decisions. Secondary objectives are assessment of clinical value of HER2-PET for the referring clinician; correlation of HER2-PET with standard…
The aim of this study is to evaluate androgen receptor (AR) and estrogen receptor (ER) expression non-invasively by means of PET imaging with the tracers 18F-FDHT and 18F-FES. To verify the PET results, the standard diagnostic biopsy will be…
Primary goal: determine the diagnostic quality of CE-MRI scans acquired in supine positionSecundary goal: determine the accuracy of deformable image registration between prone CE-MRI and non-CE-MRI in supine position as an alternative option
The primary objective of this study is to evaluate the ability of PET-MRI ( PET, DWI and DCE-MRI) to detect and locally stage breast cancer in patients.
The aim of the study is to optimize the selection of patients with ductal carcinoma in situ (DCIS), diagnosed on core needle biopsy (CNB), for a sentinel node biopsy procedure (SNP). In addition to the usual work up patients included in this study…
Primary Objective: Examining the value of ABVS in relation to current breast imaging techniques by: - comparison of ABVS findings with MRI findings. - comparison of ABVS findings with mammography and hand-held US. Secondary Objectives: - assessment…
The aim of this pilot-study is to examine the accuracy of MRL compared to current nodal staging methods. We expect an acceptable accuracy of the MRL based on earlier studies with gadofosveset enhanced MRI in rectum cancer patients. A positive MRL…
To assess the effectivity and safety of 1.0 molar gadobutrol (Gadovist®) for breast MRI
Primary objective:To compare the specificity of multiple voxel MR spectroscopy with MRI.Secondary objective: To decrease the number of false positive diagnostic outcomes by using multiple-voxel MR-spectroscopy and therefore to reduce benign biopsies…
In the present study, we aim to perform a feasibility study to prove that 89Zirconium-bevacizumab PET scanning can indeed detect all small primary breast cancer lesions. Data from the present study may be used to design further studies with regard…