238 results
Uspio enhanced MRI (MRL) potentially has the ability to show all lymph nodes and hence provide information on metastasis in all nodes, this is in contrast with SLNB which only provides information on 1 (or a few) lymph node(s). With MRL metastases…
a) to analyze and optimize the image quality of this prototype 3D-scanner. b) to assess the potential of the 3D-scanner to detect lesions (benign and malignant) in the breast and c) to assess the potential to determine the localization of lesions in…
To study motivational and psychological aspects, aestetic outcome, and general satisfaction in two groups of women who opt for mastectomy with breast reconstruction either with autologous material using the DIEP-flap procedure or with silicon…
Investigate the consequences of axillary lymph node dissection (ALND) and sentinel lymph node procedure (SNP) regarding shoulder impairments, the activities a women still undertakes and the role of quality of life and anxiety in this in women who…
Hypothesis.In women with preeclampsia endovascular remodeling and invasion of the spiral arteries is less prominent which will result in overwhelming placental oxidative stress and pregnancy failure. Abnormal function of trophoblast and stroma cells…
Primary objective: To assess technical feasibility of lymphatic mapping in patients previously treated for primary breast cancer with prior surgery with a negative SNB. Secondary objectives: To determine lymphatic drainage pathways in patients with…
The aim of this protocol is twofold. • Firstly, we aim to combine the new response monitoring method (PET imaging) with the present technique (dynamic CI-MRI imaging) in order to discriminate between favourable and unfavourable response of the…
The main objective of this study is to determine the performance of whole breast scanning with ultrasound (WBUS), combined with MRI, in a yearly breast cancer screening program for high-risk women, compared to the current practice of the combination…
Ergonomics and function of the imaging system - the NIRF imaging system should not interfere with the standard Sentinel Lymph Node mapping procedure and used safely by the surgeon while detection of ICG takes place. Duration: 1,5 hour clinical…
- Assess the feasibility of the nipple aspiration procedure- Gain experience in methods and techniques of nipple aspiration - Identify factors that are associated with the fluid yielding status of nonlactating women- Assess the discomfort…
Pilot for determining the feasibility and image quality of high resolution Tc99m-SestaMIBI imaging of lumpectomy specimens for detection, localization, and quantification of resection margins.
The main objective of this study is to define the optimal dose of fluorescent tracer for intraoperative detection of tumor delineation during breast cancer surgery.
Primary aim:A comparison of a hybrid CGC with planar lymphoscintigraphy in SN detection for breast cancer. Secondary aims:- A comparison of a hybrid CGC with an intraoperative gamma probe in SN detection in breast cancer. - To study if it is…
Feasibility ex vivo Homologous Recombination Deficiency (HRD) test in advanced breast cancer disease
The primary objective of this study is determining the feasibility of the ex vivo HRD test in metastatic lesions of different sites among breast cancer patients who will start treatment with chemotherapy. The sites of metastatic lesions that will be…
The primary objective is to evaluate the clinical utility of experimental PET scans, in the setting of metastasized breast cancer (MBC) at first presentation. Secondary objectives: - The relation between progression free survival (PFS, defined as…
Our study aim is to assess whether it is feasible to remove small breast cancers completely using the BLES system under US guidance.
Primary Objectives:Use 89Zr-Trastuzumab to characterise the in vivo biodistribution using PET imaging in the primary tumour and distant metastases.Comparie the uptake in patients with Her2/neu positive breast cancer to patients with HER2/neu…
To assess the clinical safety and feasibility of the MaMaLoc technique: a novel magnetic localisation technique for intra-operative lesion localisation.
The purpose of the study is to determine the added value of multivoxel Magnetic Resonance Spectroscopy (MRS) in women with increased risk for breast cancer and equivocal enhanced breast lesions detected at screening with standard Dynamic Contrast…
Primary goal: to assess the accuracy of a supine magnetic resonance imaging (MRI)-guided electromagnetic navigation system used for tumor marker implantation in breast cancer patients.Secondary goal: to assess the variability in target volume…