31 results
Primary objective: To evaluate whole body distribution of 89Zr-pembrolizumab in patients with locally advanced or metastatic melanoma or NSCLC. Secondary objectives: i) To evaluate pharmacokinetics of 89Zr-pembrolizumab; ii) To assess the…
To study whether either early 18F-FDG or 18F-FLT PET is superior in detecting response to treatment with the combination of vemurafenib plus cobimetinib (GDC-0973) compared to standard response assessment with CT and to evaluate whether, and which,…
1. Test if serum levels of S-100B are elevated in serum that contains frozen adipocytes2. Test if serum levels of S-100B are elevated in serum that was collected with a troublesome venipuncture 3. Test if serum levels of S-100B are lower in the…
To compare ICG-99Tc-nanocolloid to 99mTc-Senti-Scint for sentinel node mapping in patients with malignant melanoma of the trunk, an extremity or in the head and neck area.
To establish the diagnostic value of clinical diagnosis to predict the histological BCC subtype and compare this by the diagnostic accuracy of PB to determine the subtype of BCC in the subsequent SE/MMS specimen.
With this pilot study we aim to prove that our optical spectroscopy system can provide accurate identification of nerve tissue during surgery.
The objective of the present study is to investigate the possbility to discriminate between actinic keratoses an dcutaneous squamous cell carcinoma with fluorescence diagnosis.
The aim of this study is to study whether the symptom pain is a diagnostic marker for a cutaneous squamous cell carcinoma.
To identify biological effects of bevacizumab therapy and to visualize distribution kinetics of 111In-bevacizumab with gamma-camera imaging.
Identification of predictive parameters for colitis in melanoma patients treated with immunotherapy.
To identify predictive parameters for colitis in melanoma patients treated with immunotherapy
The principal objective of the study is to determine if the performance of the new technique (magnetic tracer and magnetometer) is equivalent to the performance of the standard technique (patent blue dye and radioistope; or radioisotope alone). The…
To study the sensitivity of the combined gamma probe and US guided FNA compared to the gold standard histology of the surgically removed SNB. Secondary aims 1) to study the identification rate of this technique 2) to study possible differences in…
Primary Objective: to explore the feasibility and to identify potential hurdles of in vivo assessment of pigmented skin lesions by Raman spectroscopy.Secondary Objective(s): - to compare in vivo measurements with the results obtained by ex vivo…
In the future, the determination of CTCs and ctDNA in the CSF could be a new quantitative method for the anti-tumor response assessment of systemic or intrathecal therapy (as opposed to CSF cytology, which is subjective and not a quantitative method…
To prospectively document the introduction of the sentinel node procedure for bulky cT1-T2N0 nasal vestibule carcinoma in patients at risk of nodal involvement.
The primary objective of this study is to optimize a workflow for identification of circulating melanoma cells in LA using flow cytometry. Secondary objectives include the detection of known mutations in different CMC subsets.
Primary Objectives- To investigate the impact of dose reduction of 18F-FDG on image quality of PET-MRII in patients with melanoma. Secondary Objectives- To determine the maximum reduction of radiation dose for 18F-FDG PET-MRI as compared to…
To investigate the added value of OCT as a non-invasive tool for the diagnosis of recurrent BCC.
Primary Objective: - Investigate whether recirculating tumor-associated tissue macrophages (TiMas), as well as circulating melanoma cells can be detected using high-end flow cytometry methods in peripheral blood from melanoma patients.Secondary…
The primary objective of this study is to evaluate the feasibility and diagnostic accuracy of pre-operative MRI scanning using SPIO compared to lymphoscintigraphy (LS) and single-photon emission computed tomography/computed tomography (SPECT/CT)…