114 results
1. To what extend does hypoxia occur in cervical cancer and what is the intra- and intertumor heterogeneity?2. To what extend does proliferation occur in cervical cancer and what is the intra- and intertumor heterogeneity?3. Does co-localization of…
To investigate whether advanced-stage prostate cancer patients have circulating prostate (cancer)-specific CD8+ T-lymphocytes
The purpose of our study is to prospectively establish in vivo in patients proof of principle for the RUNMC MR imaging-compatible robotic system designed for image-guided prostatic needle intervention.
The primary objectives of our study are: - Determining the long-term predictive value of a positive HPV test for (pre)malignant cervical disease.- Determining the long-term protective value of a negative HPV test. - Determining the long-term…
This is a pilotstudy after characterising prostate tissue by using DCE-MRI in patients with a localised prostate cancer.The relation between DCE-MRI and vasculature and oxygenation will be investigated as a preparation for further studies.
The primary objective is to gain experience with primary radiochemotherapy and to determine the locoregional response rate at 12 weeks after radiochemotherapy and after groin dissection for cN1,2 patients.
The primary objective is to determine the positive and negative predictive value of an hrHPV test after treatment for the development of recurrent (cervical) disease on the long term.
Visualization of the MGU and it*s borders on MRI scans of women without cervical cancer.
1. Compare generic and pelvic-floor-specific QOL in patients who have been treated or gynaecologic cancer to that of patients without cancer attending a gynaecologist for pelvic floor symptoms.2. Examine how many and which patients receive or have…
Primary objective:- to identify risk factors for cardiovascular disease following treatment for testicular cancerSecondary objective:- to investigate genetic polymorphisms that are potentially involved in the development of treatment-related…
The objective of this study is to determine how well two different doses of ipilimumab work in patients with prostate cancer who are no longer responding to hormone therapy (castration resistant), and whom have the best radiographic progression-…
This study is designed to determine quality of care for the discussion of fertility concerns and cryopreservation after diagnosis and treatment for TC. The consult with health care providers where patients are informed about the risk of impaired…
To assess the PD, PK and safety of the Zoreline 10.8 mg goserelin subcutaneous (SC) implant.
The primary objective of this study is to further evaluate the safety and effectiveness of the MRI-guided TULSA-PRO device intended to ablate prostate tissue of patients with localized, organ-confined prostate cancer.
The purpose of our study is to prospectively establish in vivo in patients proof of principle for real-time lesion targeting during MR-guided prostate biopsy using an iPad inside the MR-room. Additionally, we will evaluate the time to first biopsy…
To determine whether prostate biopsies processed with the SmartBX system result in more and better interpretable material.
The primary objective is to determine the optimal pharmacokinetic model of 68Ga-PSMA PET/CT, so 68Ga-PSMA PET/CT results can be quantified in prostate cancer.The secondary objectives are to determine whether the optimal kinetic model of 68Ga-PSMA…
Primary Objective: To assess the detection rate of 18 F-FDHT PET/CT in men with recurrent prostate cancer after radiotherapy who are candidates for local salvage treatment.Secondary Objective(s): To assess the detection rate and accuracy of 18 F-…
To validate two novel genomic biomarkers that provide information with respect to the presence of PCa, disease aggressiveness, and progression towards recurrent and metastatic disease.