106 results
Zie pagina 39-40 van het protocol MO22923 versie 2, 26 Mei 2011
This study is performed to compare the diagnostic performance and cost-effectiveness of different methods in the preoperative characterization of ovarian masses: RMI compared toa) simple ultrasound-based rules as a first step test and subjective…
Primary Objective: To assess whether the combination of Saline Infusion Sonohysterography (SIS) and Endometrial Brush Biopsy (EMB) will create an innovative algorithm for diagnosing corpus uteri malignancy in postmenopausal women suffering from…
The purpose of this project is to investigate the presence and course of neo-antigen specific immunity in patients with polymerase epsilon (POLE) mutated endometrial cancer, with the intent to exploit the obtained knowledge of neo-antigen specific…
The primary objective is to investigate the quality (whether assessable by a pathologist or not) of the endometrial sample obtained by aspiration when performed directly before or after the SIS in postmenopausal women. Secondary objectives are to…
The objective of this feasibility / pilot study is to clarify the clinical performance and economic efficiency of the cervical cancer screening system which is under development at Sysmex Corp Japan. In this study, the objective should be achieved…
This study aims to identify global and local determinants of HPV vaccine acceptability, HPV vaccine uptake and compliance as well as identify logistics and programmatic issues in each country to offer the HPV vaccine, as a potential cervical cancer…
The primary objective of this study is to analyse the microenvironment of the tumour, (sentinel) lymph nodes (i.e. various T-cell populations, antigen presenting cells and myeloid-derived suppressor cells) in patients with vulvar carcinoma. The…
Determine which anaesthetic technique (general anaesthesia in combination with TAP blockade versus general anaesthesia in combination with thoracic epidural analgesia)offers the most benefits, with respect to attenuation of the surgical inflammatory…
To validate MRI for assessing craniocaudal tumor extension with histopathology using non-rigid egistration. In addition to 3 Tesla magnetic resonance T2-weighted imaging, diffusion weighted imaging (DWI) and dynamic contrast enhanced (DCE) imaging…
The aim of this study is to (i) determine non-invasive visualisation of tumour hypoxia with [18F] HX4 PET imaging in cervix carcinomas; (ii) correlate [18F] HX4 PET images with blood and tissue markers for hypoxia; (iii) investigate the quality and…
The primary objective of this study is to analyse the microenvironment of the primary tumour and sentinel and non-sentinel lymph node(s) (i.e. various T-cell populations, antigen presenting cells and myeloid-derived suppressor cells) in patients…
Primary Objective: To evaluate the diagnostic performance of MR-PET in preoperative staging and evaluation of operability of women with advanced stage epithelial ovarian cancer. Diagnostic accuracy in terms of sensitivity and specificity of MR-PET…
The aim of the present study is to identify aberrations that play a significant role in therapy response of ovarian cancer patients. RNA sequence/expression and protein expression data will be combined and correlated to the extensive clinical follow…
OBJECTIVE NOMETEC PART I: "Mapping the lymphatic drainage of the uterus: a feasibility study of the sentinel node procedure"Our aim is to find out which out of two injection methods with technetium labelled nanocolloid is the best to…
Rationale: The purpose of this project is to investigate the presence and course of natural WT1-specific and PRAME-specific immunity in EOC patients, with the intent to exploit the obtained knowledge of WT1-specific and PRAME-specific immunity for…
Primary: • To evaluate the sensitivity and specificity of DWI-MRI to identify patients who will develop local failure after radio-chemotherapy of cervix cancer.Secondary: • To evaluate the sensitivity and specificity of MRI techniques including (T2-…
In this controlled (studygroups from P05-095 will serve as controls) observational study, the effects of radiation therapy after nerve-sparing radical hysterectomy for early stage cervical cancer on sexual function, bladder and bowel function is…
Detect exfoliated cells from STICs in lavage fluid from the uterine cavity and proximal fallopian tubes
To monitor the effects of radiotherapy alone, chemoradiation and radiotherapy combined with hyperthermia on the immune response and different T cell subsets over time in patients with cervical cancer.