192 results
In this study we aim to evaluate the effectivity of the current, standard treatment of uncomplicated urinary tract infections with fosfomycin, based on urine concentrations of fosfomycin in urine in healthy volunteers after receiving a single, oral…
Monitoring and evaluation of the Dutch guideline for treatment of aHUS in children and adults during two years.
- To evaluate the bladder-preservation rate after chemoradiation - To evaluate the toxicity and complications of treatment with induction chemotherapy followed by ePLND and chemoradiation
The primary objective of this study is:- To evaluate the effect of the elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) single-tablet regimen (STR) on renal parameters at Week 24The secondary objectives of this study are:- To…
Primary Objective: To characterize the long-term safety and tolerability of AMG 416 in the treatment of SHPT in subjects with CKD on hemodialysisSecondary Objective: To characterize the long-term efficacy of AMG 416 on intact parathyroid hormone (…
The primary objective of this trial is to evaluate and describe the long-term safety of tolvaptan.
Primary objectives: To assess the feasibility of ZW800-1 in intraoperative detection of the urinary tract using the NIR fluorescence imaging system. Secondary objectives: To define the optimal dose of ZW800-1 for intraoperative imaging of the…
The first objective of this study is to evaluate the effect of standard HD with different dialysate calcium concentrations as well as HD combined with citrate-acid dialysate on the clearance of CPPs and second the effect of these different solutions…
The aim of this study is to identify the degree and direction of fluctuation from one to another renal function group within 2 months after discharge from hospital. In addition, prevalence of adaptations of the prescribed drugs that should result…
The primary objectives of the trial are to:- Evaluate the efficacy of the PCL-based bulking agent treatment as determined by the Stamey Grading System (SGS). The SGS will be determined at baseline, 3, 6, 12, 18, and 24 months follow-up. - Evaluate…
Primary Objective* To assess the association between changes in the number of nocturnal voids and change in Nocturia Sleep Quality Scale (NSQS) total score in adult subjects with nocturia due to Nocturnal Polyuria (NP)Secondary Objectives* To assess…
Hypothesis: Opsys will improve mild incontinence based on urine loss per 24 h measured by 24 h pad test.The main objective of this study is to test the effectiveness of Opsys in a group of selected subjects with minimal to mild (less than 30 g per…
A better understanding on the individual response to different albuminuria lowering drugs and a better understanding why these drugs, of which some are developed for another indication, may help to tailor optimal therapy. Therefore in this study…
The goal of this study is to analyse the effect and safety of PTNS in 20 children with persistent overactive bladder complaints refractory to standard treatment
To investigate whether the current dosing regimen of ciprofloxacin, recommended by the Dutch *Stichting Werkgroep Antibioticabeleid* (SWAB) and applied at the Academic Medical Center for patients with various degrees of renal function admitted at…
The aim is to determine the immediate effect of sacral neuromodulation on urodynamic measurements.
To evaluate BlueWind Medical RENOVATM System safety and performance in OAB patients for extended FU period of 36 months.
The aim of this study is to evaluate logistic challenges of normothermic machine perfusion in transplant candidate allocated in the ESP
Objective: The principal objective is To evaluate the long-term safety and maintenance of efficacy of BOTOX® (200 U) injected into the detrusor for the treatment of urinary incontinence caused by neurogenic detrusor overactivity in patients who have…
To evaluate the safety and efficacy of solifenacin succinate suspension once daily in children and adolescents with OAB.