42 results
Monitoring and evaluation of the Dutch guideline for treatment of aHUS in children and adults during two years.
The primary objective of this trial is to evaluate and describe the long-term safety of tolvaptan.
A better understanding on the individual response to different albuminuria lowering drugs and a better understanding why these drugs, of which some are developed for another indication, may help to tailor optimal therapy. Therefore in this study…
The purpose of this clinical study is to provide confirmation of the clinical safety and performance of the CINCOR* System in removing contrast in patients at risk of developing CIN who are undergoing percutaneous coronary procedures.
Identify and characterize factors which predict rapid progression toward, or higher frequency of, clinically relevant morbidities in ADPKD.
Aim of this study proposal· To establish whether oral phosphorus binding is able to reduce FGF23 levels in patients with CKD stage 3.· To evaluate if a reduction of serum phosphate and FGF23 improves vascular function as measured by pulse-wave-…
The aim of the study is to evaluate the safety of the Flex catheter and the effect of the renal denervation on blood pressure.
The primary aim of this study is to compare the removal of (especially protein-bound) uremic toxins between 4-hour and 8-hour HD and HDF in order to evaluate the influence of dialysis duration and of convection on the removal of uremic toxins.A…
The objective of the study is to develop a non-invasive method to detect the early signs of oncoming hypotension during haemodialysis in order to prevent these from occurring
The purpose of this clinical study is to provide confirmation of the clinical safety and performance of the CINCOR* System in patients at risk of developing CIN who are undergoing interventional percutaneous coronary procedures.Further, the data…
We want to investigate if in critically ill patients use of LMWH is associated with stable plasma levels of anti-Xa activity. Furthermore, we want to investigate if GFR and circulation influence anti-Xa activity and which complications can occur.…
The main objective of this study is to show that the basilic vein transposition in the current elderly population is superior to the brachiocubiti fistula in terms of easy cannulation and maturation. Primary outcome is one year patency We will also…
The purpose of this study is to show that participation in an exercise programme will increase the exercise tolerance, musle power and health-related quality of life and will diminish the degree of fatigue in children on dialysis.
The central hypothesis of this project is that Aliskiren causes a substantial decrease in MSNA in hypertensive patients with CKD.
In the present study, we want to investigate the effect of kidney denervation on MSNA in hypertensive patients. The central hypothesis of this project is that MSNA in hypertensive patients will decrease (or may be even normalize as in bilaterally…
The study objectives are1. to compare blood purification efficacy for postdilution HDF treatment in ULTRACONTROL mode to that of i) postdilution HDF using volume control mode, and ii) high-flux HD treatment, using in all treatments the same dialyzer…
Assess the efficacy and safety of eculizumab in pediatric patients with aHUS to control TMA as characterized by thrombocytopenia, hemolysis and renal impairment.
Assess the efficacy of eculizumab in adult patients with aHUS to control TMA as characterized by thrombocytopenia, hemolysis and renal impairment.
Primary Objective:Determination of the best surgical approach in the individual patient to achieve optimal outcome statistics (catheter survival, 30-day or in-hospital mortality and long-term mortality) Secondary Objective:Comparison of short and…
The primary objective of this study is to determine whether ACE inhibition results in an improvement of microvascular glycocalyx-thickness in patients with type 1 diabetes. The secondary objectives are to investigate whether this (hypothesized)…