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Intracytoplasmatic Sperm Injection using testicular spermatozoa in men with azoospermia; an observational study with follow-up of the offspring.

To evaluate the efficacy of TESE and to describe the risks of the TESE procedure for the men with a four year follow-up of their offspring.

153Sm-EDTMP versus docetaxel for multiple painful osseous metastases in prostate cancer

The sequential application of chemotherapy and radionuclide treatment in patients with symptomatic osseous metastasized prostate cancer. Patients with more than one painful osseous metastasis will be randomized between 153Sm-EDTMP or docetaxel 3…

Clinical and histologic effect of transrectal intraprostatic injections with botulinum toxin in patients with lower urinary tract symptoms caused by benign prostatic hyperplasia.

To determine the effect on lower urinary tract symptoms and to determine urodynamic and histologic changes after intraprostatic botulinum toxin type A injection.

Neo-adjuvant versus Adjuvant chemotherapy in Upper Tract Urothelial Carcinoma: A feasibility phase II randomized clinical trial (*URANUS*)

This study has been transitioned to CTIS with ID 2024-514991-41-01 check the CTIS register for the current data. To assess the proportion of UTUC patients with adequate renal function and fit to receive either neo- or adjuvant cisplatin-based…

The *Utrecht Prostate Cohort for cancer treatment intervention studies and long term evaluation (UPC)* study

To set up a cohort that will serve as a multi-trial platform and facilitate evaluation of new interventional treatment for prostate cancer.

Cost-effectiveness of a Non-degradable Urethral Bulking Agent as compared to Mid-urethral Sling surgery in women with Stress Urinary Incontinence

We propose a study to compare the cost-effectiveness of the new UBA to MUS surgery.