20 results
To obtain and evaluate OCT-probe recordings and to test the interaction between the OCT-probe and the robot.
The main objective is to describe the interactions between physical sensory stimulations and high-level prior assumptions that give rise to visual perception. In two secondary objectives, we will advance novel model-based neuroimaging data-analysis…
To identify eyes that show worsening and disease progression (progressor phenotypes). Primary ObjectiveTo identify *progressors* in retinal vascular disease and central retinal edema in type 2 diabetic patients with early NPDR, based on retinal…
Development and validation of the D-AI KIDS and the D-AI YA:Currently there is no standardized instrument that measures visually impaired children*s and young adults' participation based on the nine ICF-CY domains. The primary objective of this…
Primary ObjectivesThe primary objectives of this study are:* To evaluate the long-term efficacy outcomes following short-term exposure to rhIGF-1/rhIGFBP-3 versus standard neonatal care in Study ROPP-2008-01 (Section D) as assessed by ROP associated…
Investigate clinical anomalies in the intraocular tissues, especially the accommodation system, in RDEB patients.
To objectively investigate retinal function deterioration due to the inflammatory process by ERG. To investigate if risk factors for loss of ERG activity in uveitis herald more aggressive immunomodulation treatment to prevent visual loss.
Research questions:What is the current prevalence of latex allergy among operating room employees from Erasmus Medical Centre, Rotterdam? Is the sensitisation prevalence significantly lower compared to the prevalence before introducing non powdered…
The objective of this study is to establish normative data on OCT in children between the ages of 4 to 10.
The aim of this study is to compare the results of 2 methods for screening of eye function in children with the standard investigation by the orthoptist. The outcome of the tests and the time involved will be compared.Two screening methods will be…
To evaluate the natural progression of disease over time in USH1B patients using visual field testing and best corrected visual acuity.
The objective of the study is to gain a better understanding of disease progression over time in male subjects with X-linked retinitis pigmentosa (XLRP).
Our study objective is to investigate the reliability of commonly used clinical examinations and endpoints performed in patients with inherited retinal dystrophies in anticipation of future clinical trials.
To evaluate the natural progression of anatomical and functional visual parameters in genetically defined subjects with Geographic Atrophy (GA) due to Age-related Macular Degeneration (AMD).
The primary objective is to determine the incidence and severity of sicca complaints after ICI administration. The secondary objectives are: 1) to measure changes in objective measures of oral and ocular dryness after ICI administration; 2) to…
The primary objectives of this study are the following:* To prospectively characterize CEP290-related retinal degeneration and the clinical phenotype of participants with light perception to 20/50 visual acuity and with either compound heterozygous…
Our aim is to provide the fPRC with empirical data. With studying questions based on literature and practice, the project aims to provide professionals with necessary knowledge to set up early counselling. Besides, the results of the project can…
The objective of this study is to determine which problems arise from different levels of impairments in visual and auditory functions. We will especially focus on the areas of access to information, communication, fatigue and mobility.
Primary Objectives• To evaluate prognostic factors of disease progression in subjects with Stargardt disease secondary to mutation in the ABCA4 gene • To further characterize the STGD1 patient population for future interventional clinical studies
The general objective is to validate a new non-invasive retinal imaging tool that allows the identification of relevant biomarkers in the retina in degenerative diseases of the brain and the eye by scattering and absorption properties.