24 results
Now that the ProTwin study has shown an important benefit of pessary use in woman with a short cervix in twin pregnancy, long term follow-up is needed to show that there is no potential harm in using a pessary for preterm delivery prevention. We…
To examine the protective effects of a single session of high frequency rTMS over the left dorsolateral prefrontal cortex on negative mood and motivated attention.
Primary Objectives1. The primary objective of Study 1 is to evaluate the relationship of IPV and children*s symptoms and adjustment within a clinical sample of 75 families exposed to IPV and 50 comparison families, and to test whether this…
In the present study we propose two TMS experiments, in which we want to examine the brain areas crucially involved in the processing of emotional prosody in healthy right handed subjects.
This study will investigate whether odors can be conditioned to fearful events and themselves elicit fear in humans. Fear conditioning will be tested on two odors: a pleasant odor and an unpleasant odor. The research questions are 1) can odors be…
Primary Objective: The main objective is to compare the effectiveness and cost-effectiveness of Cognitive Behavioural Therapy (CBT) to psychopharmacological treatment with paroxetine in patients with Posttraumatic stress disorder (PTSD) in a…
To evaluate the effectiveness of the cognitive based behavioral psychotherapy as given by the VALK Foundation by means of psychophysiological measures.
Are there indications for differences in feasibility and adverse-effects, between a CBT group and a MBSR group in persons with recent onset schizophrenia or related disorders? Are there indications of effect on severity of distress of both…
1.Is the unilateral ultra-briefpulse stimulation used in this study as effective as briefpulse stimulation for the acute treatment of depression?2.Do the studied characteristics of the electrical stimulation -used to induce a seizure- differ in…
We hypothesized that trying to regulate negative emotions would lead to binge eating in patients with BED. Patients with BED who actively try to alter their negative emotions are unable to control or inhibit their desire to resist (fattening) food…
The aim of the present study is to test whether there is a causal relationship between expectancies regarding the effect of eating on mood, changes in mood and actual caloric intake. In order to test whether there is a causal relationship between…
Primary ObjectiveTo evaluate the effect of a single 84-mg dose of intranasal esketamine compared to placebo, on next day driving performance and repeated administration of 84 mg intranasal esketamine on same-day driving performance as assessed by…
Primary Objective: The aim of this study is to determine a cut-off score at the PQ-16 with the CAARMS for better detection of adolescents 12-18 years at risk. Secondary Objective(s): To study the course of UHR in adolescents 12-18 years over a one…
In this study we will compare the differential (cost)- effectiveness of three individual psychotherapies: short-term psychodynamic supportive psychotherapy (SPSP), affect phobia therapy (APT) and schema therapy (ST). Although these psychotherapies…
The primary objective of the study is to predict the effect of a given ecological momentary intervention (either ReApp or Imager) based on acquired baseline measures. Further, the use of DBMs to generate an objective stressor reactivity score is…
We will compare the AMPD model to the traditional (Section II) PD model with regard to patients* and clinicians* experience of the clinical utility of both models. As the AMPD model was designed to improve clinical utility, we expect that both…
In this study we will compare the (cost)- effectiveness of psychodynamic group therapy (PG) with schema-focused group therapy (SFGT) and group schema therapy (GST). The group formats differ both in amount of sessions (resp. 80, 60 and 30 sessions)…
This study has been transitioned to CTIS with ID 2024-518769-80-00 check the CTIS register for the current data. Objective 1: to conduct a pragmatic single blind randomised superiority trial (RCT) testing the following hypotheses:1. social recovery…
Primary objectives:1). Compare efficacy of Prolonged Exposure therapy (PE), Eye Movement Desensitization and Reprocessing (EMDR), and Imagery Rescripting (ImRs) with a 3-month waitlist condition (WL) in reducing posttraumatic stress disorder (PTSD)…
This study primarily aims to test the additional effect of walking during a Virtual Reality exposure treatment (3MDR) for patients with PTSD. Next, this study aims to investigate whether addressing trauma-related avoidance during 3MDR treatment is…