16 results
There are two objectives for this study: first, to find specific serum beta cell damage markers that can serve as a clinical predictive tool for beta cell allograft loss. Second, to compare quality of life and diabetes-related outcomes in patients…
The potential for risperidone to induce hyperprolactinemia in pediatric patients is well known.However, the effects of drug-induced serum prolactin elevations on growth and sexual maturation havenot been as well characterized in pediatric…
The overall objectives of CLEAR are to improve our global understanding of the longitudinal impact ofattention-deficit/hyperactivity disorder (ADHD) and contribute to the body of scientific evidence regarding thetreatment and evolution of ADHD over…
Primary Objective: The main objective is to compare the effectiveness and cost-effectiveness of Cognitive Behavioural Therapy (CBT) to psychopharmacological treatment with paroxetine in patients with Posttraumatic stress disorder (PTSD) in a…
To investigate the effects of galantamine on cognitive impairment and visual hallucinations in Parkinson`s disease, both therapeutic (direct effect) and preventive (protection against an acute increase of dopaminergic medication used by the patient…
The objective of the study is two-fold:First, we want to improve the design of the study for future extension, by critical evaluation of the efficacy, the instruments used and the outcome measures. Second, we want to assess the cognitive and…
The objective of the study is to investigate the long-termeffects of lithium on the development of children who are exposed to lithium during pregnancy.
The main objective of this study is to investigate if 800 IU or 1600 IU vitamin D is needed to reach adequate levels of vitamin D after 3 months of treatment in at least 80% of the patients with severe mental illness (patients with SMI) between 18…
The objective of this study is to investigate whether patients with a good premorbid functioning have a beter treatment response after treatment with Risperdal® Consta® than those patients with poor premorbid functioning. Premorbid functioning of…
The purpose of our study is to test the augmenting effect and mechanisms of change of exercise provided directly before in total 12 CBT sessions.
The aim of the study is to observe the changes in severity of AVH symptoms during standard treatment of CBT or antipsychotics in patients with BPD.
This study has been transitioned to CTIS with ID 2024-518101-18-02 check the CTIS register for the current data. The main objective of this project is to associate the gut microbial community with treatment efficacy (i.e., relieve in symptoms and…
The objective of this study is to examine the effect of riluzole on the glutamate/GABA balance in the brain in patients with 22q11.2DS. The secondary objective is to examine the effects of riluzole on psychotic symptoms and cognitive functioning. In…
This study (AMYPAD Diagnostic and Patient Management Study) will determine in a real-life clinical setting for whom diagnostic amyloid PET imaging is appropriate, when this is best performed, and how the resulting information is influencing…
The aim of this study is to assess the differences in the pharmacokinetic properties of clozapine and norclozapine when clozapine is used OID or BID in psychiatric patients, examining both clozapine and norclozapine concentrations and its unbound…
Preliminary guidance on how to support these patients in clinical practice will be derived. Primary objective is the change in drug concentrations in plasma (therapeutic drug monitoring) (mg/L) of the psychotropic drug after bariatric surgery (at 1…