132 results
This study offers a unique opportunity to investigate the causal role of the PAG in fear reactions. Animal research (e.g., in mice) provides reasons to suspect that this brain region is causally involved (see reviews Hagenaars et al., 2014 and…
The purpose of the study is to systematically document the signs and symptoms of sexual abuse in infants and very young children and the short-, medium-, and long-term effects of the abuse, including the effects of the persistence of pornographic…
Primary objectives:1). Compare efficacy of Prolonged Exposure therapy (PE), Eye Movement Desensitization and Reprocessing (EMDR), and Imagery Rescripting (ImRs) with a 3-month waitlist condition (WL) in reducing posttraumatic stress disorder (PTSD)…
Whether disrupting reconsolidation by a noradrenergic *-blocker provides long-term relief of PTSD symptoms in combat veterans.
To determine 1) the psychological distress and quality of life, and 2) the psychosocial impact of the pathogenic germline CDKN2A variant on lifestyle, genetic testing, skin, and pancreatic surveillance, and family planning in PV carriers and their…
The primary objective of the proposed study is to examine the feasibility and acceptability of VR-delivered exposure sessions in a therapy protocol for PTSD. The secondary objective is to test how effective the intervention is in reducing symptoms…
The project evaluates an intervention aimed at arousal regulation.The research questions are:- Is there an improvement in signaling body signals and in arousal regulation after following this program?- Does this also lead to positive changes in…
2. OBJECTIVES2.1 Primary Objective Do clients experience less anxiety and less dissociation when wearing a pressure vest during EMDR sessions than when they do not wear a pressure vest during EMDR sessions?2.2 Secondary Objective(s) Do clients…
The primary objective of this study is to derive and externally validate a prognostic screening instrument to predict individual risk to follow an adverse PTSD symptom trajectory over the course of one year following trauma based on self-report…
Feasibility is assessed after every VR-EMDR session and after treatment completion. PTSD symptoms, quality of life and self-empowerment are assessed before and after treatment.
The aim of this this study, is to test whether EMDR therapy, relative to a baseline phase, results in: 1) less social anxiety symptoms, and 2) less social avoidance symptoms
This study primarily aims to test the additional effect of walking during a Virtual Reality exposure treatment (3MDR) for patients with PTSD. Next, this study aims to investigate whether addressing trauma-related avoidance during 3MDR treatment is…
The goal of the current pilot study is to demonstrate the feasibility of hypnotherapy in AYAs as supportive treatment during active medical cancer treatment or follow-up up to 6 months after finishing medical treatment. Medical hypnotherapy will be…
The aim of this pilot study is to explore whether the intervention 'From There Towards Now' (FTTN) is effective in reducing anxiety and mood (OQ-45), obsessive-compulsive (Y-BOCS), PTSD (PCL- 5) and personality symptoms (SIPP-SF), next to…
Primary Objective: To investigate the effectiveness of imagery rescripting on factors presumed to underlie the disorder, according to schema theory, and on OCD and BDD symptoms and psychosis. Primary objective is the course of schema or core beliefs…
The aim of this study is to investigate the mechanisms behind and influence of the PTSS assistance dog on military veterans with PTSD and their families.
To investigate the dose-response relationship, test-retest reliability and tolerance to repeated exposure of the 35% carbon dioxide experimental panic challenge in CO2-sensitive healthy volunteers as measured with the PSL-IV total Score, VAS Fear,…
The primary objective is to determine the effects of iPE on the PTSD diagnosis, on the self-rated and clinician-rated severity of PTSD symptoms. The secondary objectives are to determine the effects on psychotic symptoms, depression symptoms,…
To test the hypotheses that EMDR therapy will significantly (1) reduce anxiety in persons with epilepsy-related anxiety symptoms, from pre-treatment to post-treatment, (2) reduce seizure frequency and severity and will (3) improve quality of life…