67 results
The main objective of this study is to investigate sex and gender differences in the prospective relationship between experienced stressors, craving and alcohol use during treatment and early recovery of AUD. The secondary objectives of this study…
Objective of the quantitative and qualitative study:To gain knowledge about which transdiagnostic factors are associated with dropout from and outcome of intensive high-specialty treatment.Objective of the pilot study:To gain insight into the role…
To determine the targets for an intervention aimed at reducing revictimization after trauma-treatment by means of a co-creation session. A secondary objective is to gain insight into the interpersonal revictimization history of people currently in…
Primary Objective: To explore the acceptability and feasibility of rTMS added to exposure with response prevention and/or medication as an intervention in youth with OCD and/or GTS. Secondary Objective(s): - To explore the effects of added rTMS on…
Clinical validation of capillary microsampling with finger pricks for olanzapine. The validation method is performed in accordance with the EM guideline. In this process, the analytical methods are assessed for selectivity, carry-over, lower limit…
The main objectives are to investigate whether our product is suitable for the target group, to identify barriers to wider implementation in mainstream care, and to gather patient experience and feedback. We want to know if patients perceive the…
To unravel cocaine metabolism in patients with cocaine use disorder for the purpose of potentially improving bioanalytical tests for cocaine use
In the project *Monitoring Outcomes of Pharmacotherapy (MOPHAR), an infrastructure will be created in which - using standardised protocols - longitudinal monitoring data will be collected regarding Routine Outcome Monitoring (ROM), medication usage…
The primary objective of this study is to expand the knowledge about pregnant women with PTSD (symptomatology). Pregnant women with PTSD (symptomatology) will be described, ass wel ass the pregnant women who develop PTSD (symptomatology) during…
* To examine the effects and interactions of individual and environmental factors on the onset and course of mental health problems in adolescents and young adults. * To examine the effects and interactions of individual and environmental factors on…
The main objective of this study is to assess the feasibility, acceptability, and effectiveness of four imagery intervention techniques adapted from the protocol of Holmes (2019) for auditory vocal hallucinations. We are primarily interested in…
(Also see METC- protocol)Primary Objective:To investigate the effectiveness of the SPACE treatment to improve family accommodation and OCD symptoms.Secondary Objective: To explore mechanisms of change (in OCD symptoms) for the effectiveness of the…
This cohort study aims to explain why some children develop well and others fail to thrive in society. To this purpose, we examine how neurocognitive development mediates the association between developmental changes in biological, child-related and…
The goal of this study is to test the effectiveness of a short-term VR shame intervention (SHINE-VR) for adolescents suffering from PTSD after having experienced sexual abuse. The primary objectives of this study are:1) To assess the effect of SHINE…
The main objective of this project is to study the prevalence of autoantibodies against the NMDA-r, AMPA-r, GABAB-r and VGKC-complex (LGI-1 and Caspr-2) in patients with an early onset psychotic disorder. Patients suffering from stable but also…
This cohort study aims to explain why some children develop well and others fail to thrive in society. To this purpose, we examine how neurocognitive development mediates the association between developmental changes in biological, child-related and…
The purpose of the study is to investigate the effectiveness of oxygen therapy in headache after ECT.No research has been conducted into a non-medical treatment of headache after ECT. Oxygen therapy is potentially a quick, inexpensive, and safe way…
Primary research questions:(1) What is the rate of persistent DSM-5 moderate to severe SUD from adolescence to young adulthood among youth in addiction treatment?(2) What is the prognostic value of a general population-based set of predictors of…
Aim of this assessment is to explore the course (persistence, remission and onset) of AH and to investigate associations with other psychic experiences, anxiety and depressive symptoms, risk factors (trauma, cannabis), protective factors (coping…
The objective of the current study is to assess feasibility and acceptance of the pre-treatment assessments (PRoSPECTs feasibility study).