95 results
To compare acylated and unacylated ghrelin concentrations in pregnant women with GD and without GD.
Study i)Select the most valid and feasible accelerometer for measuring habitual physical activity in children with a mitochondrial disorderStudy ii)Measure the test-retest reliability of this instrument
To describe the wound related complication rate in post-bariatric body contouring surgery patients who are treated according to a new guideline and assess the factors associated with a higher complication rate.
To study feasibility, reliability and validity of a specific set of outcome measures in children with mitochondrial myopathy.
This study will form the basis for future studies that are planned to investigate chemosensory disturbances in elderly and testicular cancer patients who are undergoing cisplatin based chemotherapy within the University Medical Center Groningen.…
The purpose of this observational study is to investigate the adherence during 2 months in adolescents with type 1 diabetes on subcutaneous insulin pump therapy. The main outcome measure will be the amount of insulin bolusses and glucose…
To investigate the dynamic changes in bone marrow adiposity during the menstrual cycle as assessed by Dixon*s Quantitative Chemical Shift Imaging (QCSI) measurements and to determine the role of estrogen in these changes.
Including the collection of biological biomarkers into a social survey such as SHARE is of important scientific value as it opens up multiple research possibilities: -Identification of causal relationships: biological biomarkers can help to…
The aim of the study is to determine whether prenatal and current exposure to environmental chemicals is associated with developmental outcome in adolescents. We will investigate whether this exposure is associated with the thyroid hormone…
In this study we will assess the optimal analytical conditions for routine laboratory GDM screening in the Netherlands, possible discrepancies in clinical outcome due to (pre)analytical variation and the applicability of POCT testing in GDM…
To perform 31P-MRS during and after exercise using a specifically designed probe to determine variations in energy metabolism along the TA muscle in healthy humans subjects.
1) elucidate the role of the postural CO decrease on cerebral hemodynamics, 2) test the influence of posture, ageing and T2DM on the CO-VO2 relationship. Furthermore, 3) we want to determine the shape of the CO-VO2 relationship.
To standardize the procedures and analyses to support evaluation of glucose dependent insulin secretion in Type 2 Diabetes Mellitus in subjects with Type 2 Diabetes.
To identify eyes that show worsening and disease progression (progressor phenotypes). Primary ObjectiveTo identify *progressors* in retinal vascular disease and central retinal edema in type 2 diabetic patients with early NPDR, based on retinal…
The study has two objectives:1) Is chronic fatigue a clinically relevant issue in patients with DM type 1?Chronic fatigue will be considered a clinically relevant issue if:(a): the proportion chronically fatigued DM type 1 patients is at least 25%(b…
Hypotheses: - The five tastants (sour, sweet, salt, bitter and umami) each induce GI peptide release by human duodenal mucosa ex vivo. - The five tastants (sour, sweet, salt, bitter and umami) each induce GI peptide release by human ileal mucosa ex…
To investigate the time difference between the blood glucose excursion and the subsequent appearance of cerebral 13C glucose after intravenous glucose loading.
The aim of the study is to quantify the requirement of threonine in preterm infants. We hypothesize that the current estimations for preterms are too high.
1. To determine the 10 year course and outcome of Anorexia Nervosa.2. To explore predictors of outcome in Anorexia Nervosa.
The first aim of this study is to extend clinical knowledge on NPC. This has several reasons:1) The heterogeneous clinical presentation of NPC makes extensive clinical knowledge amongst physicians a prerequisite in preventing diagnostic delay.…