16 results
To assess whether a change in BMD as detected big DXA (gold standard) is comparable with the decline measured by the achilles method
To investigate the dynamic changes in bone marrow adiposity during the menstrual cycle as assessed by Dixon*s Quantitative Chemical Shift Imaging (QCSI) measurements and to determine the role of estrogen in these changes.
The objective of the study is to investigate vertebral bone marrow fat fraction and bone mineral density during surgery induced weight loss.
The first objective of this study is to evaluate the effect of standard HD with different dialysate calcium concentrations as well as HD combined with citrate-acid dialysate on the clearance of CPPs and second the effect of these different solutions…
We examine whether the calcium intake from food in postmenopausal women with an ID suffice to the quantity calcium intake that is advised by the NHG-standard. If the conclusion of this study will be that the population is eating less calcium than is…
The primary objective is to assess bone structure parameters and bone strength by high resolution peripheral quantitative CT evaluation (HRpQCT) and physical activity in relation with subsequent falls, fractures and mortality in patients with a…
Primary objective1.To determine the characteristics, frequency and severity of vascular, metabolic and hormonal side effects of angiogenesis inhibitors and EGFR inhibitors.Secondary objectives1.To investigate if steroid profile, indol profile,…
The aim of this study is to assess the sensitivity, specificity and predictive value of the Dutch osteoporosis case-finding instrument as a tool for vertebral fracture case-finding in a primary health care setting. Furthermore the impact of a…
The aim of this study is to determine the quantity of vitamin D3 in anterior adipose tissue in pregnant women, and to determine the influence of exposure to sunlight and the consumption of fatty fish on vitamin D storage in anterior adipose tissue.…
To demonstrate the feasibility to induce an effective, predictable and sustained decrease in FGF23 level in CKD stage I-IV patients, without inducing hypophosphatemia using a stepped treatment regimen aiming at restricting phosphate uptake.
Objective: To obtain data to be used for designing a larger scale study on the incidence of 25OHD levels below the recommended level of 50 nmol/l in children in Murmansk, Russia and Groningen, the Netherlands.
The main objective is to validate serum calcification propensity as a read-out for vascular calcification and the secondary objective is to identify determinants of vascular calcification (progression).
This study aims to determine the effect of nocturnal versus daytime cyclic infusion of parenteral nutrition in adult chronic intestinal failure patients on bone turnover, glucose metabolism, nitrogen balance, sleep and wake rhythm and clock genes…
Primary:• Determine the biochemical manifestations of ADH1/2 over timeSecondary:• Understand renal health of participants with ADH1/2 • Determine incidence of nephrocalcinosis and/or nephrolithiasis in ADH1/2 participants• Understand bone health in…
Clinical feasibility of the urine collection device, indicated by staff and parents.
Primary objectivesPart 1:• To establish a corrected standardized gradient of fracture risk using the POROUS R3C ultrasound device based on prevalent fractures.Part 2:• To establish a corrected standardized gradient of fracture risk using the POROUS…