362 results
To establish biomarkers in nipple aspirate fluid, follow them in time and link them to breast cancer development at its earliest stage in women at high risk for breast cancer. Threshold values of biomarkers will be determined that point to a…
Biobanking of testicular biopsies from azoospermic men undergoing testicular sperm extraction (TESE)
Biobanking of a testis biopsy from men with azoospermia who undergo a TESE procedure to allow investigation for understanding the etiology of male infertility, research about normal and aberrant male gamete formation in its natural environment of…
During this feasibility study will be analysed if endometrial cells by using tampons can be obtained during surveillance of women with Lynch syndrome and first degree relatives at 50% risk of the gene mutation who get annual surveillance in the…
The main objective is to evaluate the safety and tolerability of Ad[I/PPT-E1A] as an adjuvant treatment for localised prostate cancer before radical prostatectomy. A secondary objective is to explore the histopathological and immunological effects…
Our primary objective is to develop an easily assayable germline-based panel of biomarkers to aid in selecting prostate cancer patients for management with active surveillance. As a secondary objective, we tend to incorporate potentially promising…
Determine which anaesthetic technique (general anaesthesia in combination with TAP blockade versus general anaesthesia in combination with thoracic epidural analgesia)offers the most benefits, with respect to attenuation of the surgical inflammatory…
The aim of our study will be to evaluate patients* perspective on sexual and fertility healthcare currently provided by renal care providers. Furthermore we will identify patients* wishes and views upon this important part of renal healthcare and…
The primary objective is to investigate the quality (whether assessable by a pathologist or not) of the endometrial sample obtained by aspiration when performed directly before or after the SIS in postmenopausal women. Secondary objectives are to…
Primary Objective: To identify dropout rates at all stages of fertility care at the fertility centres of Isala in Zwolle, Erasmus MC in Rotterdam, Reinier de Graaf group in Voorburg, Elisabeth Twee Steden in Tilburg, the St Antonius Ziekenhuis in…
To assess the effects of vaginal prolapse surgery on microcirculatory parameters measured in the vaginal wall with the use of incident dark field (IDF) imaging (Cytocam).
To determine the value of a post coital test in the basic fertility work up in WHO class II subfertile women ovulatory after clomiphene citrate (CC).
We will investigate whether Chlamydia IgG antibody presence and titers in vaginal swabs (mucosa-CAT) are comparable to antibodies found in serum (serum-CAT), and as such could serve as a marker for a past Chlamydia infection with an enhanced risk of…
To compare vascular density and angiogenic factors in normal endometrium and endometrium covering submucous fibroids in patients with submucous fibroids.
Main objective of this study is to test the feasibility and to determine the short and medium term histological cancer control of focal therapy using MR-guided focal laser ablation therapy in the treatment of localised prostate cancer. Secondary…
To assess short-term and long-term complications of mumps-associated orchitis in vaccinated men
Primary Objective: Examining the value of ABVS in relation to current breast imaging techniques by: - comparison of ABVS findings with MRI findings. - comparison of ABVS findings with mammography and hand-held US. Secondary Objectives: - assessment…
This study is to answer two questions. First the acceptability and ease of use of the modified version of he Delphi Screener in general and in different body positions. Second the confirmation of a sufficient yield of cervicovaginal cells by self…
Primary Objective:To assess the ability of BR55 to identify area(s) of VEGFR2 expression in human prostate by ultrasound molecular imaging on the basis of a visual score in comparison with histopathology analysis (location based on expression of…
Primary objectives:To confirm the lack of effect of 0.5 mg sublingual testosterone on physiological and subjective measures of sexual arousal in women with HSDD. Secondary objective:To confirm the lack of effect of 0.5 mg sublingual testosterone on…
The aim of the research up till now was, during a number of months, to examine a total of 500 participants referred for mammography to the AMC. The different parameters which are relevant to compression were measured. Particularly the influence of…