362 results
The primary objective is efficacy of atezolizumab in advanced penile cancer patients measured by progression-free survival.
Primary objective:1. To evaluate the safety and tolerability of the [18F]fluoro-PEG-folate PET tracer2. To determine the pharmacokinetics (protein binding, biodistribution, clearance rate) of the [18F]fluoro-PEG-folate PET tracerSecondary objectives…
The purpose of the study is to provide comparative analysis of breast imaging modalities of BCT (nu:view) compared to MRI.
The objective of this study is to establish the effectiveness and confirm the safety of the VizAblate System in ablating symptomatic uterine fibroids.
The main objective of the SOPI study is to select the HRD test that best predicts longest PFS on PARP-i in non-BRCA1/2 EOC patients, in order to adequately select patients that will benefit from a PARP-i. Secondary objectives are: to…
In the present study the clinical feasibility and safety of MR-guided focal boost radiotherapy for patients with locally advanced prostate cancer will be evaluated.
Primary Objective: • To investigate the feasibility of utilizing PAI as a means of detecting the SLN in patients with melanoma or breast cancerSecondary Objective(s): • Determine the most effective wavelengths for detecting ICG in PAI• Investigate…
feasability of a robot-assisted laparoscopic, single colpectomy in female-to-male transgenders who already had their uterus removed.
Primary ObjectiveTo evaluate the safety of the Aqua Therapeutics Thermal Therapy Vapor Ablation System (ATTTVAS).Secondary Objectives1. To evaluate the change of menstrual blood loss (MBL).2. To evaluate the effect of MBL on the quality of life (…
This study has been transitioned to CTIS with ID 2024-511537-35-00 check the CTIS register for the current data. Phase 1• To establish the RP2D regimen by evaluation of the safety and tolerability of intravenous (IV) administration of Lutetium (…
1. What is the level of psychological distress among cervical cancer patients over time?2. What is the role of characteristics of the individual, characteristics of the environment, biological function, overall quality of life, functional status and…
In this project, we hypothesize that presence of genetic variants associated with earlier age of natural menopause might be involved in diminished responsiveness of the ovaries to exogenous FSH stimulation during IVF treatment. Furthermore, we aim…
The goal of this pilot study is to 1. Investigate the feasibility of the lymphatic mapping procedure in locally advanced cervical cancer 2. Study the agreement of the lymphatic map with the radiotherapy treatment plan. Are all lymph nodes at risk…
The primary aim of the present study is to investigate whether current standard treatment for PID is clinically effective in patients in whom Mycoplasma genitalium (MG) is present. A secondary aim of the study is to asses whether this treatment is…
Primary objective: To evaluate the safety, tolerability, and maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D) of investigational therapies in subjects with metastatic castration-resistant prostate cancer (mCRPC).Secondary objective:*…
The OPTIMUM-study aims to gain insight into the optimal timing and method for promoting sustained adherence to lifestyle and body weight recommendations in PMBC survivors.The aim of the extra measurement during the second COVID-19 lockdown is to…
The primary objective is to determine in which percentage of patients with prostate cancer with an indication for ADT, it is safe to extend the dosing interval of goserelin 10,8 mg by four weeks, before the 4th injection, using a testosterone based…
Objective:The life-time risk for POP surgery is 20%, and 30% of these women will need surgery because of a recurrence. VaginalPOP surgery (VH, SSH and MM) is the first choice surgical treatment. The numbers of uterus sparing operations (SSH andMM)…
The hormonal range of LH, FSH, AMH, inhibin B, testosterone and estradiol in girls with TS during the minipuberty and the relation of the hormone serum levels with the karyotype.
Primary: To evaluate the sensitivity and specificity of dynamic contrast enhanced (DCE-MRI) to identify patients who have increased risk of disease recurrence (local, nodal, systemic) after radio-chemotherapy of cervix cancer.Secondary: To apply…