25 results
To investigate whether it is possible to manipulate perfusion in type 3 fibroids with MR-HIFU.
Primary Objective: To assess whether the combination of Saline Infusion Sonohysterography (SIS) and Endometrial Brush Biopsy (EMB) will create an innovative algorithm for diagnosing corpus uteri malignancy in postmenopausal women suffering from…
Main objective of this study is describing the functional morphology of the microcirculation of the endometrium.
To determine which advanced image enhanced modality is the most feasible for the detection of endometriosis lesions, with respect to the specificity and sensitivity of the investigated modalities. To determine which imaging modality reveals more…
- To assess the effect of QBW251 on the pharmacokinetics of a monophasic combined oral contraceptive containing 30 µg ethinyl estradiol (EE) and 150 µg levonorgestrel (LVG).- To assess the effect of QBW251 on the pharmacodynamics of a monophasic…
To obtain the safety and effectiveness data necessary to support a Premarket Approval (PMA) Application to the U.S. Food and Drug Administration (FDA)
To compare vascular density and angiogenic factors in normal endometrium and endometrium covering submucous fibroids in patients with submucous fibroids.
The purpose of this study is to quantify the amount of menstrual bleeding in participants with menorrhagia and its correlation to the overall impact of health as measured by the Menorrhagia Questionnaire.
The objective of this study is to establish the effectiveness and confirm the safety of the VizAblate System in the ablation of large (> 5 cm) symptomatic uterine fibroids.
Primary Objective: test the feasibility of Dynamic-CE-MRI using Ablavar ® as contrast agent to detect peritoneal endometriosis in women.Secondary Objective(s): # To assess the image quality of Ablavar ®-enhanced MRI in comparison to unenhanced MRI…
To measure the impact of the two opposite communication styles (warm, empathic and cold, formal) on the neurophysiological changes (endogenous dopamine release) in the human brain using positron emission tomography (PET) neuroimaging. This is an…
This research proposal has multiple aims for research in women with WHO I, II or III status, including extended care and general health assessment, diagnosis/etiology, assessment of best approach/treatment, cardiovascular risk assessment, and…
The primary objective of this study is to evaluate the safety and effectiveness of Doppler guided Uterine Artery Occlusion (D-UAO) as treatment for the reduction of fibroid-associated symptoms.
To study if a hysteroscopic resection a safe and effective treatment is for intermittend/post menstrual bloodloss or spotting.
This study primarily aims to get insight in the intraoperative nociceptive state of the patient as an index of the amount of pain stimuli comparing the three modes of hysterectomy. Next to this, by measuring pre-, intra- and postoperative stress…
To establish the safety and effectiveness of the Sonata System in the treatment of symptomatic uterine fibroids.
To determine the feasibility of Fusion MRI-ultrasound for the uterus and ovary.To determine if Fusion MRI-ultrasound is more accurate for the diagnosis of endometiosis then MRI or ultrasound alone.
To provide clinical data on clinical efficacy to support embolisation of uterine fibroids using Embozene microsferes
The objective of the OPEN Study is to document the presence or absence of intrauterine adhesions after treatment with the Sonata System when used in women with submucous and/or transmural fibroids in accordance with product labeling.An evaluation…
The objective of this monocenter, single-blinded, randomised controlled trial is to evaluate the effectiveness and cost-effectiveness of the Duckbill polyp snare in comparison with the hysteroscopic morcellator.Hypothesis: We hypothesize that snare…